HPLC Determination of Four Derivatives of Benzene

Yun Wang; Yan-Li Xi

doi:10.14233/ajchem.2015.18092

Issue

Vol. 27 No. 2 (2015): Vol 27 Issue 2

Issue Published : January 10, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

HPLC Determination of Four Derivatives of Benzene

https://doi.org/10.14233/ajchem.2015.18092

Yun Wang

School of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang 524048, P.R. China

Yan-Li Xi

School of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang 524048, P.R. China

Corresponding Author(s) : Yun Wang

wangyun203@hotmail.com

Asian Journal of Chemistry, Vol. 27 No. 2 (2015): Vol 27 Issue 2
Article Published : January 10, 2015

Abstract

In the paper, the HPLC determination condition for four derivatives of benzene including 1,4-phthalaldehyde, nitroxinil, 1,2,4,5-tetrafluoro-benzene and 2-chloro-4'-fluoroacetophenone has been improved. The trifluoroacetic acid has been applied in the HPLC determination condition for the four compounds for the first time. The ODS-C₁₈ (4.6 × 150 mm, 5 μm) column was used, The mobile phase was a mixture of acetonitrile-0.1 % trifluoroacetic acid aqueous solution (55:45 or 50:50). The wavelength of determination was 254 nm. The four compouds have been separated throughly with the HPLC determination condition. This method is accurate, simple and rapid and suitable to laboratory and industry.

Keywords

Trifluoroacetic acid Four derivatives of benzene HPLC

Wang, Y., & Xi, Y.-L. (2015). HPLC Determination of Four Derivatives of Benzene. Asian Journal of Chemistry, 27(2), 781–782. https://doi.org/10.14233/ajchem.2015.18092

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References

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References

Z.H. Chen, C.J. Zheng, L.P. Sun and H.R. Piao, Eur. J. Med. Chem., 45, 5739 (2010); doi:10.1016/j.ejmech.2010.09.031.

B.L. Li, P.H. Li, X.N. Fang, C.-X. Li, J.-L. Sun, L.-P. Mo and Z.-H. Zhang, Tetrahedron, 69, 7011 (2013); doi:10.1016/j.tet.2013.06.049.

A.B.A. Boxall, Comparative and Veterinary Pharmacology, Handbook of Experimental Pharmacology, Vol. 199, pp. 291-314 (2010).

T. Grabowski, J.J. Jaroszewski and W. Piotrowski, Toxicol. In Vitro, 24, 953 (2010); doi:10.1016/j.tiv.2010.01.003.

A. Streitwieser, D.Z. Wang, M. Stratakis, A. Facchetti, R. Gareyev, A. Abbotto, J.A. Krom and K.V. Kilway, Can. J. Chem., 76, 765 (1998); doi:10.1139/v98-069.

J. Leroy, B. Schöllhorn, J.L. Syssa-Magalé, K. Boubekeur and P. Palvadeau, J. Fluor. Chem., 125, 1379 (2004); doi:10.1016/j.jfluchem.2004.04.008.

J.M. Cobb, N. Grimster, N. Khan, J.Y.Q. Lai, H.J. Payne (née Gold), L.J. Payne, T. Raynham and J. Taylor, Tetrahedron, 43, 7557 (2002); doi:10.1016/S0040-4039(02)01810-5.

D. Zhu, B.A. Hyatt and L. Hua, J. Mol. Catal. B, 56, 272 (2009); doi:10.1016/j.molcatb.2008.05.012.

M. Rostami, A.R. Khosropour, V. Mirkhani, I. Mohammadpoor-Baltork, M. Moghadam and S. Tangestaninejad, Comptes Rendus Chim., 14, 869 (2011); doi:10.1016/j.crci.2011.02.003.

G. Milhaud, G. Keck and D. Courtot, Vet. Res. Commun., 107 (1983); doi:10.1007/BF02228603.

A.S. Kende, J.J. Wade, D. Ridge and A. Poland, J. Org. Chem., 39, 931 (1974); doi:10.1021/jo00921a017.

A.J. Heeger, F. Wudl and C.W. Dirk, US Patent 4,626,586 (1986).

M. Schlosser and E. Marzi, Chem. Eur. J., 11, 3449 (2005); doi:10.1002/chem.200401094.

M. Stratakis, P.G. Wang and A. Streitwieser, J. Org. Chem., 61, 3145 (1996); doi:10.1021/jo9516401.

A. Meudt, R. Wisdom, C. Boehm et al., US Patent 0206826 A1 (2008).

K. Takeba and M. Matsumoto, Jpn. J. Public Health, 39, 75 (1992).

T. Hirano, T. Arai and M. Kinouchi, US Patent 0115695 A1 (2006).

K. Li, L.N. Foresee and J.A. Tunge, J. Org. Chem., 70, 2881 (2005); doi:10.1021/jo0477650.

M.A. Deeg, D.R. Humphrey and S.H. Yang, J. Biol. Chem., 267, 18573 (1992).

M. Hasegawa, A. Isogai, F. Onabe and M. Usuda, J. Appl. Polym. Sci., 45, 1857 (1992); doi:10.1002/app.1992.070451020.

A. Otaka, T. Koide, A. Shide and N. Fujii, Tetrahedron Lett., 32, 1223 (1991); doi:10.1016/S0040-4039(00)92050-1.

E.J. Bourne, M. Stacey, J.C. Tatlow and J.M. Tedder, J. Chem. Soc., 2976 (1949); doi:10.1039/JR9490002976.

A.S. Castanet, F. Colobert and P.E. Broutin, Tetrahedron Lett., 43, 5047 (2002); doi:10.1016/S0040-4039(02)01010-9.

Z. Zhong, Q. Ji and J.A. Zhang, J. Pharm. Biomed. Anal., 51, 947 (2010); doi:10.1016/j.jpba.2009.10.001.

M. Ciulu, S. Solinas, I. Floris, A. Panzanelli, M.I. Pilo, P.C. Piu, N. Spano and G. Sanna, Talanta, 83, 924 (2011); doi:10.1016/j.talanta.2010.10.059.

G. Venkatasami and J.R. Sowa Jr., Anal. Chim. Acta, 665, 227 (2010); doi:10.1016/j.aca.2010.03.037.

C. Guarino, F. Fuselli, A.L. Mantia and L. Longo, Food Chem., 127, 1294 (2011); doi:10.1016/j.foodchem.2011.01.086.

Issue

Vol. 27 No. 2 (2015): Vol 27 Issue 2

HPLC Determination of Four Derivatives of Benzene

Corresponding Author(s) : Yun Wang

Abstract

Keywords

Full Article

Download Citation

References

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