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Vol. 27 No. 2 (2015): Vol 27 Issue 2

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Electrochemical Behavior and Determination of Glycyrrhizic Acid at Glassy Carbon Electrode Modified with Graphene

https://doi.org/10.14233/ajchem.2015.16966
Gao-Feng Shi
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Jin-Mei Su
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Guo-Ying Wang
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Hai-Xiao Liu
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Jian Miao
School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, P.R. China
Zhe-Ru Shi
College of life and Environmental Sciences, Shanghai Normal University, Shanghai 201400, P.R. China

Corresponding Author(s) : Gao-Feng Shi

gaofengshi_lzh@163.com

Asian Journal of Chemistry, Vol. 27 No. 2 (2015): Vol 27 Issue 2

Abstract

A simple and rapid electrochemical method is developed for the determination of glycyrrhizic acid, based on the excellent properties of graphene. The graphene-modified glassy carbon electrode constructed and the electrochemical behaviour of glycyrrhizic acid at the electrode is investigated in detail. In 0.2 mol/L pH 7 phosphate buffer solution, the redox peak currents of glycyrrhizic acid increased significantly at graphene modified glassy carbon electrode compared with bare glassy carbon electrode, indicating that graphene possessed electrocatalytic activity towards glycyrrhizic acid. The experimental conditions were optimized and the kinetic parameters were investigated. Under the optimal experimental conditions, the oxidation peak current was proportional to glycyrrhizic acid concentration in the range from 3.12 × 10-8 to 1 × 10-6 mol/L with the correlation coefficient of 0.9915. The detection limit was 2 × 10-8 mol/L. Using the proposed method, glycyrrhizic acid was successfully determined in water samples, suggesting that this method can be applied to determine glycyrrhizic acid in different liquorices.

Keywords

Graphene Glycyrrhizic acid Modified electrode Behavior
Shi, G.-F., Su, J.-M., Wang, G.-Y., Liu, H.-X., Miao, J., & Shi, Z.-R. (2015). Electrochemical Behavior and Determination of Glycyrrhizic Acid at Glassy Carbon Electrode Modified with Graphene. Asian Journal of Chemistry, 27(2), 473–476. https://doi.org/10.14233/ajchem.2015.16966
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