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Vol. 27 No. 11 (2015): Vol 27 Issue 11

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One Pot Synthesis and Antimicrobial Activity of Substituted 2-Aminothiazoles

https://doi.org/10.14233/ajchem.2015.19092
Abdullah Sulaiman Al-Ayed
Department of Chemistry, College of Sciences and Arts at Al-Rass, Qassim University, P.O. Box 53, Kingdom of Saudi Arabia

Corresponding Author(s) : Abdullah Sulaiman Al-Ayed

asaaied@qu.edu.sa

Asian Journal of Chemistry, Vol. 27 No. 11 (2015): Vol 27 Issue 11

Abstract

In this work, we described a preparation of substituted 2-aminothiazoles by two different methods using a one-pot procedure and starting from methoxymethylene-3-aryl-thiourea (2). The synthesized 2-aminothiazoles (5a-h) were characterized on the basis of elemental analysis and their spectral (IR, 1H NMR and 13C NMR) data and evaluated their biological activities. The majority of compounds were found to exhibit significant antimicrobial activity.

Keywords

Methoxymethylene-3-aryl-thiourea 2-Aminothiazoles Antimicrobial activity
Sulaiman Al-Ayed, A. (2015). One Pot Synthesis and Antimicrobial Activity of Substituted 2-Aminothiazoles. Asian Journal of Chemistry, 27(11), 4081–4084. https://doi.org/10.14233/ajchem.2015.19092
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