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Vol. 35 No. 1 (2023): Vol 35 Issue 1

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Antimicrobial and Antioxidant Study of Some Newly Synthesized Chalcones and Cyclohexenone Derivatives

https://doi.org/10.14233/ajchem.2023.24057
M. Sapnakumari
Department of Chemistry, St. Agnes Centre for Post Graduate Studies and Research, Mangalore-575002, India
K. Divya
Post Graduate Department of Chemistry, B.M.S. College for Women, Autonomous, Basavanagudi, Bengaluru-560004, India
K.B. Aswin
Department of Chemistry, St. Agnes Centre for Post Graduate Studies and Research, Mangalore-575002, India
J. Dalin
Department of Chemistry, St. Agnes Centre for Post Graduate Studies and Research, Mangalore-575002, India

Corresponding Author(s) : M. Sapnakumari

sapna@stagnescollege.edu.in

Asian Journal of Chemistry, Vol. 35 No. 1 (2023): Vol 35 Issue 1

Abstract

Chalcones and cyclohexenone derivatives obtained from various substituted aldehydes and substituted acetophenones are described. Chalcones were obtained by the Claisen-Schmidt condensation reaction of aldehydes with substituted acetophenones. Base catalyzed cyclocondensation of ethyl acetoacetate to chalcones under microwave irradiation leads to the formation of cyclohexenone derivatives. The prepared compounds are characterized by IR, 1H NMR and 13C NMR spectral methods. These are screened for their antimicrobial activity against Staphylococcus aureus, Escherichia coli, Aspergillus niger, Aspergillus flavus and also, for their antioxidant properties.

Keywords

Chalcone Microwave assisted synthesis Cyclocondensation Antimicrobial study Antioxidant study
Sapnakumari, M., Divya, K., Aswin, K., & Dalin, J. (2022). Antimicrobial and Antioxidant Study of Some Newly Synthesized Chalcones and Cyclohexenone Derivatives. Asian Journal of Chemistry, 35(1), 114–118. https://doi.org/10.14233/ajchem.2023.24057
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