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Vol. 30 No. 8 (2018): Vol 30 Issue 8

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Synthesis, Characterization and Biological Activities of Mercury(II) Ternary Complexes of 2-Substituted Benzothiazoles Derivatives

https://doi.org/10.14233/ajchem.2018.21301
Manmohan Singh Chauhan1
1ASAS, Department of Chemistry, Amity University Rajasthan, Jaipur-303 002, India 2Department of Chemistry, Malaviya National Institute of Technology, Jaipur-302 017, India 3Department of Chemistry, JECRC University, Jaipur-303 905, India 4Hyderabad Institute of Technology and Management, Hyderabad-501 401, India *Corresponding author: E-mail: narenlamba5@gmail.com
Mitlesh Kumari Yadav2
1ASAS, Department of Chemistry, Amity University Rajasthan, Jaipur-303 002, India 2Department of Chemistry, Malaviya National Institute of Technology, Jaipur-302 017, India 3Department of Chemistry, JECRC University, Jaipur-303 905, India 4Hyderabad Institute of Technology and Management, Hyderabad-501 401, India *Corresponding author: E-mail: narenlamba5@gmail.com
Aruna Sharma3
1ASAS, Department of Chemistry, Amity University Rajasthan, Jaipur-303 002, India 2Department of Chemistry, Malaviya National Institute of Technology, Jaipur-302 017, India 3Department of Chemistry, JECRC University, Jaipur-303 905, India 4Hyderabad Institute of Technology and Management, Hyderabad-501 401, India *Corresponding author: E-mail: narenlamba5@gmail.com
Shradha Binani4
1ASAS, Department of Chemistry, Amity University Rajasthan, Jaipur-303 002, India 2Department of Chemistry, Malaviya National Institute of Technology, Jaipur-302 017, India 3Department of Chemistry, JECRC University, Jaipur-303 905, India 4Hyderabad Institute of Technology and Management, Hyderabad-501 401, India *Corresponding author: E-mail: narenlamba5@gmail.com
Narendra Pal Lamba1
1ASAS, Department of Chemistry, Amity University Rajasthan, Jaipur-303 002, India 2Department of Chemistry, Malaviya National Institute of Technology, Jaipur-302 017, India 3Department of Chemistry, JECRC University, Jaipur-303 905, India 4Hyderabad Institute of Technology and Management, Hyderabad-501 401, India *Corresponding author: E-mail: narenlamba5@gmail.com

Asian Journal of Chemistry, Vol. 30 No. 8 (2018): Vol 30 Issue 8

Abstract

Biological important ternary complexes of type [HgL(A-A)] [where L = 2-(2'-hydroxynaphthyl)benzothiazole (APBT), 2-(2'-hydroxyphenyl)benzothiazole (HPBT), 2-(2'-mercapto-phenyl)benzothiazole (MPBT)] (A = glycine or alanine) have been synthesized and characterized by m.w. determination, magnetic measurements, infrared and NMR studies. A tetrahedral geometry has been proposed for the present mercury(II) complexes. All the complexes are coloured, thermally stable, monomeric and non-electrolytic in nature. The ligands and their metal complexes showed biological activity against pathogenic fungi Aspergillus niger and Fusarium oxysporum. The antifungal activity data revealed that mercury(II) complexes are found more fungi-toxic than the parent ligands.

Keywords

Benzothiazole Amino acids Mercury(II) complexes Antifungal activity.
Singh Chauhan1, M., Kumari Yadav2, M., Sharma3, A., Binani4, S., & Pal Lamba1, N. (2018). Synthesis, Characterization and Biological Activities of Mercury(II) Ternary Complexes of 2-Substituted Benzothiazoles Derivatives. Asian Journal of Chemistry, 30(8), 1777–1780. https://doi.org/10.14233/ajchem.2018.21301
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