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Vol. 34 No. 5 (2022): Vol 34 Issue 5, 2022

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in vitro Analysis of Citric Acid Crosslinked and Juglans regia Extract Loaded Hydrogel for Biomedical Applications

https://doi.org/10.14233/ajchem.2022.23576
Mohammad Amir Qureshi
Department of Applied Sciences & Humanities, Faculty of Engineering & Technology, Jamia Millia Islamia, New Delhi-110025, India ; Department of Chemistry, Faculty of Natural Science, Jamia Millia Islamia, New Delhi-110025, India
Nahid Nishat
Department of Chemistry, Faculty of Natural Science, Jamia Millia Islamia, New Delhi-110025, India
Fehmeeda Khatoon
Department of Applied Sciences & Humanities, Faculty of Engineering & Technology, Jamia Millia Islamia, New Delhi-110025, India

Corresponding Author(s) : Mohammad Amir Qureshi

maq248@gmail.com

Asian Journal of Chemistry, Vol. 34 No. 5 (2022): Vol 34 Issue 5, 2022

Abstract

Herbal medicines are a familiar source of therapeutic agents for the medicaments of infections in various countries these days. In this work, biological study of citric acid crosslinked hydrogel loaded with Juglans regia leaves extract against 5 standard bacterial and fungal strains. The FTIR and FESEM results exhibited that leaves extract stick on the surface of hydrogel and it does not reacted with the functional groups of used polymers. The obtained results of MTT assay against L929 mouse fibroblasts cell line showed that hydrogel was biocompatible. Highest minimum inhibitory concentration was found in case of S. typhi, E. coli and C. albicans. P. aeruginosa and C. albicans were the most susceptible strains, while E. coli and S. typhi were the most resistant strains.

Keywords

Chitosan Poly(vinyl alcohol) Juglans regia Hydrogel Antimicrobial studies
Amir Qureshi, M., Nishat, N., & Khatoon, F. (2022). in vitro Analysis of Citric Acid Crosslinked and Juglans regia Extract Loaded Hydrogel for Biomedical Applications. Asian Journal of Chemistry, 34(5), 1297–1302. https://doi.org/10.14233/ajchem.2022.23576
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