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A New Cytotoxic Stilbenoid from Arundina graminifolia
Corresponding Author(s) : Xue-Mei Gao
Asian Journal of Chemistry,
Vol. 26 No. 8 (2014): Vol 26 Issue 8
Abstract
A new stilbenoid, gramniphenol K (1) was isolated from Arundina graminifolia. Its structure was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. The cytotoxicity of gramniphenol K was evaluated against five human tumor cell lines, and it showed cytotoxicity against A549, SHSY5Y and MCF7 cells with IC50 values of 6.2, 7.5 and 4.7 μM, respectively.
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References
X.Q. Chen and S.W. Gale, Floral of China; Science Press: Beijing, Vol. 25, pp 315 (2009).
Anonymous, Chinese Medicinal Herbs: Vol. Dai Yao; Shanghai Science and Technology Press: Shanghai, pp. 116 (2005).
M.F. Liu, Y. Han, D.M. Xing, Y. Shi, L.Z. Xu, L.J. Du and Y. Ding, J. Asian Nat. Prod. Res., 6, 229 (2004); doi:10.1080/10286020310001653219.
M.F. Liu, H.R. Lv and Y. Ding, J. Chin. Mat. Med., 37, 66 (2012).
M.F. Liu, Y. Han, D.M. Xing, W. Wang, L.Z. Xu, L.J. Du and Y. Ding, J. Asian Nat. Prod. Res., 7, 767 (2005); doi:10.1080/102860204100016890181.
M.F. Liu, D.M. Zhang and Y. Ding, J. Chin. Mat. Med., 30, 353 (2005).
Q.F. Hu, B. Zhou, J.M. Huang, X.M. Gao, L.D. Shu, G.Y. Yang and C.T. Che, J. Nat. Prod., 76, 292 (2013); doi:10.1021/np300727f.
X.M. Gao, L.Y. Yang, Y.Q. Shen, L.D. Shu, X.M. Li and Q.F. Hu, Bull. Korean Chem. Soc., 33, 2447 (2012); doi:10.5012/bkcs.2012.33.7.2447.
G.R. Pettit, A. Numata, C. Iwamoto, Y. Usami, T. Yamada, H. Ohishi and G.M. Cragg, J. Nat. Prod., 69, 323 (2006); doi:10.1021/np058075+.
A. Kovács, A. Vasas and J. Hohmann, Phytochemistry, 69, 1084 (2008); doi:10.1016/j.phytochem.2007.12.005.
K. Xiao, H.J. Zhang, L.J. Xuan, J. Zhang, Y.-M. Xu and D.-L. Bai, Stud. Nat. Prod. Chem, 34, 453 (2008); doi:10.1016/S1572-5995(08)80032-4.
M.A. Zaki, P. Balachandran, S. Khan, M. Wang, R. Mohammed, M.H. Hetta, D.S. Pasco and I. Muhammad, J. Nat. Prod., 76, 679 (2013); doi:10.1021/np300893n.
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