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Vol. 26 No. 8 (2014): Vol 26 Issue 8

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Functionalization Reactions of Various Pyrazole-3-carboxylic Acid Chlorides with Some Ureas

https://doi.org/10.14233/ajchem.2014.16000
Ilhan Ozer Ilhan
Department of Chemistry, Faculty of Science, Erciyes University, 38039 Kayseri, Turkey
Kazim Demirkol
Department of Chemistry, Faculty of Science, Erciyes University, 38039 Kayseri, Turkey
Zulbiye Onal
Department of Chemistry, Faculty of Science, Erciyes University, 38039 Kayseri, Turkey
Senem Akkoc
Department of Chemistry, Faculty of Science, Erciyes University, 38039 Kayseri, Turkey
Mehmet Cadir
Department of Chemistry, Faculty of Science, Erciyes University, 38039 Kayseri, Turkey

Corresponding Author(s) : Ilhan Ozer Ilhan

ilhano@erciyes.edu.tr

Asian Journal of Chemistry, Vol. 26 No. 8 (2014): Vol 26 Issue 8

Abstract

The 1H-pyrazole-3-carboxylic acids 2 or their remarkably stable acid chlorides 3 can easily be converted into the corresponding 1H-pyrazole-3-carbonyl-N'-urea derivatives (5a-k) from reaction with urea nucleophiles. It has been demonstrated that with the variation in reaction conditions, the reaction changes thus leading to different products. All newly synthesized compounds were characterized by elemental analysis, FT-IR, 1H and 13C NMR spectral data. All compounds were compared with their previous analogues.

Keywords

Furan-2 3-dione Pyrazole-3-carboxylic acid Cyclic oxalyl compounds Pyrazole-3-carboxylic acid chlorides
Ozer Ilhan, I., Demirkol, K., Onal, Z., Akkoc, S., & Cadir, M. (2014). Functionalization Reactions of Various Pyrazole-3-carboxylic Acid Chlorides with Some Ureas. Asian Journal of Chemistry, 26(8), 2365–2368. https://doi.org/10.14233/ajchem.2014.16000
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