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Vol. 26 No. 1 (2014): Vol 26 Issue 1

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Farmanol: A New Dammarane Methoxytriterpenediol from Nepeta suavis

https://doi.org/10.14233/ajchem.2014.15344
Farman Ullah Khan
Department of Chemistry, University of Science and Technology, Bannu-28100, Pakistan
Javid Hussain
Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Nizwa, Oman
Ihsan Ullah Khan
Department of Fundamental and Applied Sciences, Centre of Ionic Liquid, University of Technology Petronas, Perak, Malaysia
Nawshad Muhammad
Department of Biotechnology, University of Science and Technology, Bannu-28100, Pakistan
Syed Badshah
Department of Chemistry, Gomal University, D.I. Khan, Pakistan
Muhammad Waqar Aslam
Department of Chemistry, University of Science and Technology, Bannu-28100, Pakistan
Saleem Jan
Department of Chemistry, University of Science and Technology, Bannu-28100, Pakistan
Hizbullah Khan
Department of Chemistry, University of Science and Technology, Bannu-28100, Pakistan
Rehmat Ali Khan
Department of Biotechnology, University of Science and Technology, Bannu-28100, Pakistan
Hidayatullah Khan
Department of Biotechnology, University of Science and Technology, Bannu-28100, Pakistan

Corresponding Author(s) : Nawshad Muhammad

nawshadchemist@yahoo.com

Asian Journal of Chemistry, Vol. 26 No. 1 (2014): Vol 26 Issue 1

Abstract

Farmanol, a new dammarane methoxytriterpenediol (1), was isolated from the chloroform soluble portion of the whole plant of Nepeta suavis Stapf. In addition, the known pentacyclictriterpene, 2a-acetoxy-3b-hydroxy-olean-12-en-28-oic acid (2) and the diterpenenepetanoic acid (3) have been isolated for the first time from this species. The structure of the dammarane methoxytriterpenediol (1) was determined by comprehensive analysis of its 1D (1H and 13C NMR) and 2D NMR (COSY, HMQC and HMBC) spectra and HREIMSl data.

Keywords

Nepeta suavis Labiatae Dammarane methoxytriterpenediol
Ullah Khan, F., Hussain, J., Ullah Khan, I., Muhammad, N., Badshah, S., Waqar Aslam, M., … Khan, H. (2013). Farmanol: A New Dammarane Methoxytriterpenediol from Nepeta suavis. Asian Journal of Chemistry, 26(1), 119–121. https://doi.org/10.14233/ajchem.2014.15344
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References
  1. W.H. Lewis, Medical Botany (Plants Affecting Man’s Health). Wiley-Interscience Publication/John Wiley & Sons, New York, (1977)p. 257.
  2. L.M. Perry, Medicinal Plants of East and Southeast Asia: Attributed Properties and Uses. MIT Press, Cambridge, MA,(1980) p. 620.
  3. A. Sattar, V. Bankova, A. Kujumgiev, A. Galabov, A. Ignatova, C. Todorova and S. Popov, Pharmazie, 50, 62 (1995).
  4. L. Verotta, F. Orsini, M. Tato, N.A. El-Sebakhy and S.M. Toaima, Phytochemistry, 49, 845 (1998); doi:10.1016/S0031-9422(97)00869-8.
  5. L.O.A. Manguro, I. Ugi and P. Lemmen, Chem. Pharm. Bull. (Tokyo), 51, 483 (2003); doi:10.1248/cpb.51.483.
  6. C. Pakhathirathien, C. Karalai, C. Ponglimanont, S. Subhadhirasakul and K. Chantrapromma, J. Nat. Prod., 68, 1787 (2005); doi:10.1021/np0502793.
  7. C.H. Jiang, R. Fukuoka, F. Aoki, T. Tanaka and I. Kouno, Chem. Pharm. Bull. (Tokyo), 47, 257 (1999); doi:10.1248/cpb.47.257.
  8. K. Zou, S. Zhu, C. Tohda, Cai and K. Komatsu, J. Nat. Prod., 65, 346 (2002); doi:10.1021/np010354j.
  9. A. Ahmed, M. Asim, M. Zahid, A. Ali and V.U. Ahmad, Chem. Pharm. Bull. (Tokyo), 51, 851 (2003); doi:10.1248/cpb.51.851.
  10. B.S. Siddiqui and M. Kardar, Phytochemistry, 58, 1195 (2001); doi:10.1016/S0031-9422(01)00329-6.
  11. S. Siddiqui, F. Hafeez, S. Begum and B.S. Siddiqui, J. Nat. Prod., 51, 229 (1988); doi:10.1021/np50056a006.
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Author Biography

Farman Ullah Khan, Department of Chemistry, University of Science and Technology, Bannu-28100, Pakistan

 

 

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