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Vol. 26 No. 24 (2014)

Copyright (c) 2014 Jinquan Gao, Zongxiao Li*, Weiwei Zhao

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Thermodynamic Properties of Cyclophosphamide in Citric Acid Solution

https://doi.org/10.14233/ajchem.2014.16936
Jinquan Gao
Department of Chemistry and Chemical Engineering, Baoji University of Liberal Arts and Science, Baoji 721013, Shaanxi, P.R. China *Corresponding author: E-mail: mingtian8001@163.com
Zongxiao Li*
Department of Chemistry and Chemical Engineering, Baoji University of Liberal Arts and Science, Baoji 721013, Shaanxi, P.R. China *Corresponding author: E-mail: mingtian8001@163.com
Weiwei Zhao
Department of Chemistry and Chemical Engineering, Baoji University of Liberal Arts and Science, Baoji 721013, Shaanxi, P.R. China *Corresponding author: E-mail: mingtian8001@163.com

Corresponding Author(s) : Jinquan Gao

Asian Journal of Chemistry, Vol. 26 No. 24 (2014)

Abstract

The dissolution behaviors of cyclophosphamide in citric acid solution were studied by a microcalorimetric method, The measured integral and differential heat of solution was used to build equations of the solute and the heat, so that dissolution thermodynamic equations, Dsol Hm were achieved, The results show that, using the thermodynamic parameters of microcalorimetric method cyclophosphamide is simple and feasible. The method provides strong data support for the clinical application of cyclophosphamide.

Keywords

Cyclophosphamide Thermodynamics Microcalorimetric Citric acid Method.
Gao, J., Li*, Z., & Zhao, W. (2014). Thermodynamic Properties of Cyclophosphamide in Citric Acid Solution. Asian Journal of Chemistry, 26(24), 8649–8650. https://doi.org/10.14233/ajchem.2014.16936
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