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Vol. 26 No. 23 (2014)

Copyright (c) 2014 B. Pejin1, T. Kartali2, B. Stanimirovic3, M. Karaman2

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Avarol Effectively Inhibits Bacillus cereus Growth

https://doi.org/10.14233/ajchem.2014.17640
B. Pejin1
1University of Belgrade, Institute for Multidisciplinary Research - IMSI, Department of Life Sciences, Kneza Viseslava 1, 11030 Belgrade, Serbia 2University of Novi Sad, Faculty of Sciences, Department of Biology and Ecology, Trg Dositeja Obradovica 2, 21000 Novi Sad, Serbia 3Institute MOL Ltd, Nikole Tesle 15, 22300 Stara Pazova, Serbia *Corresponding author: E-mail: brspjn@gmail.com; boris.pejin@imsi.rs
T. Kartali2
1University of Belgrade, Institute for Multidisciplinary Research - IMSI, Department of Life Sciences, Kneza Viseslava 1, 11030 Belgrade, Serbia 2University of Novi Sad, Faculty of Sciences, Department of Biology and Ecology, Trg Dositeja Obradovica 2, 21000 Novi Sad, Serbia 3Institute MOL Ltd, Nikole Tesle 15, 22300 Stara Pazova, Serbia *Corresponding author: E-mail: brspjn@gmail.com; boris.pejin@imsi.rs
B. Stanimirovic3
1University of Belgrade, Institute for Multidisciplinary Research - IMSI, Department of Life Sciences, Kneza Viseslava 1, 11030 Belgrade, Serbia 2University of Novi Sad, Faculty of Sciences, Department of Biology and Ecology, Trg Dositeja Obradovica 2, 21000 Novi Sad, Serbia 3Institute MOL Ltd, Nikole Tesle 15, 22300 Stara Pazova, Serbia *Corresponding author: E-mail: brspjn@gmail.com; boris.pejin@imsi.rs
M. Karaman2
1University of Belgrade, Institute for Multidisciplinary Research - IMSI, Department of Life Sciences, Kneza Viseslava 1, 11030 Belgrade, Serbia 2University of Novi Sad, Faculty of Sciences, Department of Biology and Ecology, Trg Dositeja Obradovica 2, 21000 Novi Sad, Serbia 3Institute MOL Ltd, Nikole Tesle 15, 22300 Stara Pazova, Serbia *Corresponding author: E-mail: brspjn@gmail.com; boris.pejin@imsi.rs

Corresponding Author(s) : B. Pejin1

Asian Journal of Chemistry, Vol. 26 No. 23 (2014)

Abstract

This work extends in vitro screening of antibacterial activity of avarol on four selected pathogenic bacteria associated with psoriasis (Bacillus cereus, Clostridium sporogenes, Enterococcus faecalis and Staphylococcus aureus). Avarol exhibited a moderate activity with minimum inhibitory and minimum bactericidal concentrations ranged from 0.78-1.56 and 3.12-18.75 μg/mL, respectively. It proved to be more effective against B. cereus in comparison to the both positive controls applied, gentamycin and ampicillin. According to the experimental data, this marine natural product may inspire development of new antibiotics with an enhanced therapeutic index, at first place those targeting B. cereus.

Keywords

Porifera Dysidea avara Marine natural product Antibacterial activity Psoriasis.
Pejin1, B., Kartali2, T., Stanimirovic3, B., & Karaman2, M. (2014). Avarol Effectively Inhibits Bacillus cereus Growth. Asian Journal of Chemistry, 26(23), 8255–8256. https://doi.org/10.14233/ajchem.2014.17640
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