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Vol. 26 No. 20 (2014)

Copyright (c) 2014 Mecit Ozdemir1, Mehmet Sonmez2

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Antioxidant Activity, Synthesis and Characterization of Schiff Base Ligand ‘asasp’ and Metal Complexes

https://doi.org/10.14233/ajchem.2014.17699
Mecit Ozdemir1
1Chemistry Department, Faculty of Arts and Science, University of Kilis 7 Aralik, Kilis, Turkey 2Chemistry Department, Faculty of Arts and Science, University of Gaziantep, Gaziantep, Turkey *Corresponding author: Fax: +90 348 8142663; Tel: +90 348 3488142662; E-mail: mecitozdemir@kilis.edu.tr
Mehmet Sonmez2
1Chemistry Department, Faculty of Arts and Science, University of Kilis 7 Aralik, Kilis, Turkey 2Chemistry Department, Faculty of Arts and Science, University of Gaziantep, Gaziantep, Turkey *Corresponding author: Fax: +90 348 8142663; Tel: +90 348 3488142662; E-mail: mecitozdemir@kilis.edu.tr

Corresponding Author(s) : Mecit Ozdemir1

Asian Journal of Chemistry, Vol. 26 No. 20 (2014)

Abstract

In the present work, the synthesis and structural characterization of a novel Schiff base ligand derived from 2-acetyl pyridine and L-aspartic acid dimethyl ester and its metal complexes have been reported. All the synthesized compounds were characterized by using various spectral techniques like ESI-MS, FT-IR, 1H NMR, 13C NMR, UV-visible spectra, elemental analysis and ICP-OES analyses. The ligand and metal ions reacted to form in the 2:1 or 1:1 (M:L) ratio as found from the elemental analyses and the general stoichiometry was determined [L(Cu)2(AcO)4] and [LM(H2O)2]2Cl·nH2O where M = Co(II), Ni(II), Ni(II) and L = asasp and n = 1 or 2. On the basis of analytical data, a possible structure for the copper(II) complex is tetrahedral and those for the Co(II), Ni(II) and Mn(II) complexes are octahedral. The ligand and its metal complexes were tested for their possible antioxidant potentials. Comparison of antioxidant assays were investigated by using two reference molecules, vitamin C and quercetin. The complexes showed significant activities in these in vitro antioxidant assays compared to the reference (quercetin and vitamin C) and Ni(II)-complex exhibited a promising antioxidant activity.

Keywords

Antioxidant activity Metal complexes Schiff base ligand.
Ozdemir1, M., & Sonmez2, M. (2014). Antioxidant Activity, Synthesis and Characterization of Schiff Base Ligand ‘asasp’ and Metal Complexes. Asian Journal of Chemistry, 26(20), 7009–7015. https://doi.org/10.14233/ajchem.2014.17699
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