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Copyright (c) 2014 R. Thilakam, V. Jayamani*
This work is licensed under a Creative Commons Attribution 4.0 International License.
Synthesis, Spectrochemical and Antimicrobial Activity of 2-Amino-7,9-diaryl-6-methyl-8-(2¢amino-1¢3¢4¢-thiadiazolyl)methyl-thia-3,4,8-triazaspiro[4,5]dec-2-ene
Corresponding Author(s) : R. Thilakam
Asian Journal of Chemistry,
Vol. 26 No. 20 (2014)
Abstract
New heterocyclic ketoesters dithiosemicarbazone and corresponding spiro-1,3,4-thiadiazolines are prepared using 2,6-diaryl piperidones as substrates. The synthesized compounds are charactersised by elemental analysis, spectral and analytical data. They are also screened for their antibacterial and antifungal activity against E. coli and A. niger, respectively.
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- B.M. Trost and D. Lee, J. Am. Chem. Soc., 110, 6556 (1988).
- B.M. Trost and D.W.C. Chen, Am. Chem. Soc., 118, 12541 (1996).
- G.A. Elsaraf, Indian J. Chem., 31B, 167 (1992).
- C.S. Andonia and S. Dham, J. Indian Chem. Soc., 69, 169 (1992).
- M. Rajopadhye and F.D. Popp, J. Heterocycl. Chem., 24, 1637 (1987).
- T.B. Wei, H. Liu, J.H. Hu, M.L. Li, W.X. Xiu, L.Z. Yang and Y.M. Zhang, Indian J. Chem., 45B, 2754 (2006).
- S.K. Jain and P. Mishra, Indian J. Chem., 43B, 184 (2004).
- V. Jatav, P. Mishra, S. Kashaw and J.P. Stables, Eur. J. Med. Chem., 43, 1945 (2008).
- V. Padmavathi, T.V. R. Reddy and K. Reddy, Indian J. Chem., 46B, 818 (2007).
- V. Padmavathi, J.M. Reddy, C.V. Subbiah and Padmaja, Indian J. Chem., 45B, 808 (2006).
- S. Balasubramanian, C. Ramalingam and S. Kabilan, Indian J. Chem., 41B, 2402 (2002).
- R.M. Silverstin, G.C. Bassler and T.C. Morrill, Spectrometric Identification of Organic Compounds, John Wiley & Sons, edn 4, p. 122, (1998).
- K. Pandiarajan, M. Sabapathy and K. Kumar, Indian J. Chem., 26B, 624 (1987).
- D.K. Shukla and S.P. Srivastava, Indian J. Chem., 47B, 463 (2008).
- T.R. Rawat and S.P. Srivastava, Indian J. Chem., 37B, 91 (1998).
- G.L. Plourde and B.B. Fisher, Molecules, 7, 315 (2002).
- G.L. Plourde and N.J. English, Molecules, 10, 1335 (2005).
- C.R. Noller and V. Baliah, J. Am. Chem. Soc., 70, 3853 (1948).
- R. Sevim and K. M. Sevgi, Pharm. J., 16, 130 (2012).
References
B.M. Trost and D. Lee, J. Am. Chem. Soc., 110, 6556 (1988).
B.M. Trost and D.W.C. Chen, Am. Chem. Soc., 118, 12541 (1996).
G.A. Elsaraf, Indian J. Chem., 31B, 167 (1992).
C.S. Andonia and S. Dham, J. Indian Chem. Soc., 69, 169 (1992).
M. Rajopadhye and F.D. Popp, J. Heterocycl. Chem., 24, 1637 (1987).
T.B. Wei, H. Liu, J.H. Hu, M.L. Li, W.X. Xiu, L.Z. Yang and Y.M. Zhang, Indian J. Chem., 45B, 2754 (2006).
S.K. Jain and P. Mishra, Indian J. Chem., 43B, 184 (2004).
V. Jatav, P. Mishra, S. Kashaw and J.P. Stables, Eur. J. Med. Chem., 43, 1945 (2008).
V. Padmavathi, T.V. R. Reddy and K. Reddy, Indian J. Chem., 46B, 818 (2007).
V. Padmavathi, J.M. Reddy, C.V. Subbiah and Padmaja, Indian J. Chem., 45B, 808 (2006).
S. Balasubramanian, C. Ramalingam and S. Kabilan, Indian J. Chem., 41B, 2402 (2002).
R.M. Silverstin, G.C. Bassler and T.C. Morrill, Spectrometric Identification of Organic Compounds, John Wiley & Sons, edn 4, p. 122, (1998).
K. Pandiarajan, M. Sabapathy and K. Kumar, Indian J. Chem., 26B, 624 (1987).
D.K. Shukla and S.P. Srivastava, Indian J. Chem., 47B, 463 (2008).
T.R. Rawat and S.P. Srivastava, Indian J. Chem., 37B, 91 (1998).
G.L. Plourde and B.B. Fisher, Molecules, 7, 315 (2002).
G.L. Plourde and N.J. English, Molecules, 10, 1335 (2005).
C.R. Noller and V. Baliah, J. Am. Chem. Soc., 70, 3853 (1948).
R. Sevim and K. M. Sevgi, Pharm. J., 16, 130 (2012).