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Vol. 26 No. 16 (2014): Vol 26 Issue 16

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Antioxidant Activity and Antioxidant Mechanism of Brazilin and Neoprotosappanin from Caesalpinia sappan Lignum

https://doi.org/10.14233/ajchem.2014.16282
Feng-Zheng Chen
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China; These authors contributed equally to this work
Qi Zhao
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China; These authors contributed equally to this work
Jun Yan
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China
Xiao-Qiang Guo
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China
Qin Song
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China
Qian Yao
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China
Xiao-Jun Gou
Key Laboratory of Meidicinal and Edible Plant Resources Development of Sichuan Education Department, Chengdu University, Chengdu 610106, P.R. China

Corresponding Author(s) : Xiao-Jun Gou

jmee@cdu.edu.cn

Asian Journal of Chemistry, Vol. 26 No. 16 (2014): Vol 26 Issue 16

Abstract

The compounds, brazilin and neoprotosappanin, have been isolated from Caesalpinia sappan Lignum. The structures were charaterized by NMR spectra. The antioxidant activity of brazilin and neoprotosappanin were evaluateded by using free radical scavenging assays, namely 1,1'-diphenyl-2-picrylhydrazyl. The IC50 values of brazilin and neoprotosappanin are 0.067 and 0.375 μg/mL, respectively, much higher than the IC50 of vitamin C, 0.542 μg/mL. The result shows that brazilin and neoprotosappanin possess powerful antioxidant activity, which can be used as function-rich antioxidants and whose application promising are very extensive.

Keywords

Caesalpinia sappan Lignum Brazilin Neoprotosappanin Antioxidant activity Antioxidant mechanism
Chen, F.-Z., Zhao, Q., Yan, J., Guo, X.-Q., Song, Q., Yao, Q., & Gou, X.-J. (2014). Antioxidant Activity and Antioxidant Mechanism of Brazilin and Neoprotosappanin from Caesalpinia sappan Lignum. Asian Journal of Chemistry, 26(16), 4979–4981. https://doi.org/10.14233/ajchem.2014.16282
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