Copyright (c) 2014 AJC
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A New Chromone from the Stems of Cassia fistula and Its Anti-Tobacco Mosaic Virus Activity
Corresponding Author(s) : Xuemei Gao
Asian Journal of Chemistry,
Vol. 26 No. 15 (2014): Vol 26 Issue 15
Abstract
A new chromone 8-methoxy-2,2-dimethyl-7-(2-oxopropyl)-2,3-dihydrochromen-4-one (1) was isolated from the stems of Cassia fistula. Its structures was elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compound 1 was evaluated for its anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 exhibit potential anti-TMV activity with inhibition rates of 23.5 %.
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References
V. Duraipandiyan and S. Ignacimuthu, J. Ethnopharmacol., 112, 590 (2007); doi:10.1016/j.jep.2007.04.008.
S. Rajan, D.S. Baburaj, M. Sethuraman and S. Parimala, Ethnobotany, 6, 19 (2001).
J. Ma, L.X. Zhang and Y.H. Guan, Chin. J. Ethnomed. Ethnopharm, 5, 178 (2004).
K.A. Abo, A.A. Adeyemi and A.O. Sobowale, Afr. J. Med. Med. Sci., 30, 9 (2001).
S. Aurapa and G. Wandee, Int. J. Biomed. Pharm. Sci, 3, 42 (2009).
P. Sartorelli, S.P. Andrade, M.S. Melhem, F.O. Prado and A.G. Tempone, Phytother. Res., 21, 644 (2007); doi:10.1002/ptr.2131.
Y.H. Kuo, P.H. Lee and Y.S. Wein, J. Nat. Prod., 65, 1165 (2002); doi:10.1021/np020003k.
S.L. Jothy, Z. Zakaria, Y. Chen, Y.L. Lau, L.Y. Latha, L.N. Shin and S. Sasidharan, Molecules, 16, 7583 (2011); doi:10.3390/molecules16097583.
W. Zhao, X.Y. Zeng, T. Zhang, L. Wang, G.Y. Yang, Y.K. Chen, Q.F. Hu and M.M. Miao, Phytochem. Lett., 6, 179 (2013); doi:10.1016/j.phytol.2012.12.006.
Q. Hu, M. Miao, W. Zhao, T. Zhang, L. Wan, G. Yang, Y. Chen and D. Mou, Heterocycles, 85, 2485 (2012); doi:10.3987/COM-12-12557.
Q.F. Hu, B. Zhou, X.M. Gao, L.Y. Yang, L.D. Shu, Y.Q. Shen, G.P. Li, C.T. Che and G.Y. Yang, J. Nat. Prod., 75, 1909 (2012); doi:10.1021/np300395m.
Q.F. Hu, B. Zhou, J.M. Huang, X.M. Gao, L.D. Shu, G.Y. Yang and C.T. Che, J. Nat. Prod., 76, 292 (2013); doi:10.1021/np300727f.