Copyright (c) 2014 AJC
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A New Chromone from Stems of Cassia fistula and Its Anti-Tobacco Mosaic Virus Activities
Corresponding Author(s) : Yanqing Ye
Asian Journal of Chemistry,
Vol. 26 No. 14 (2014): Vol 26 Issue 14
Abstract
A new chromone, 5-hydroxy-2,2-dimethyl-7-(2-oxopropyl)-2,3-dihydrochromen-4-one (1) was isolated from the stems of Cassia fistula. Its structure was elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 1 was evaluated for its anti-tobacco mosaic virus (anti-TMV) activity. The results showed that 1 exhibit potential anti-TMV activity with inhibition rate of 16.8 %.
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References
V. Duraipandiyan and S. Ignacimuthu, J. Ethnopharmacol., 112, 590 (2007); doi:10.1016/j.jep.2007.04.008.
S. Rajan, D.S. Baburaj, M. Sethuraman and S. Parimala, Ethnobotany, 6, 19 (2001).
J. Ma, L.X. Zhang and Y.H. Guan, Chin. J. Ethnomed. Ethnopharm., 5, 178 (2004).
K.A. Abo, A.A. Adeyemi and A.O. Sobowale, Afr. J. Med. Med. Sci., 30, 9 (2001).
S. Aurapa and G. Wandee, Int. J. Biomed. Pharm. Sci, 3, 42 (2009).
P. Sartorelli, S.P. Andrade, M.S. Melhem, F.O. Prado and A.G. Tempone, Phytother. Res., 21, 644 (2007); doi:10.1002/ptr.2131.
Y.H. Kuo, P.H. Lee and Y.S. Wein, J. Nat. Prod., 65, 1165 (2002); doi:10.1021/np020003k.
S.L. Jothy, Z. Zakaria, Y. Chen, Y.L. Lau, L.Y. Latha, L.N. Shin and S. Sasidharan, Molecules, 16, 7583 (2011); doi:10.3390/molecules16097583.
W. Zhao, X.Y. Zeng, T. Zhang, L. Wang, G.Y. Yang, Y.K. Chen, Q.F. Hu and M.M. Miao, Phytochem. Lett., 6, 179 (2013); doi:10.1016/j.phytol.2012.12.006.
Q. Hu, M. Miao, W. Zhao, T. Zhang, L. Wan, G. Yang, Y. Chen and D. Mou, Heterocycles, 85, 2485 (2012); doi:10.3987/COM-12-12557.
Q.F. Hu, B. Zhou, X.M. Gao, L.Y. Yang, L.D. Shu, Y.Q. Shen, G.P. Li, C.T. Che and G.Y. Yang, J. Nat. Prod., 75, 1909 (2012); doi:10.1021/np300395m.
Q.F. Hu, B. Zhou, J.M. Huang, X.M. Gao, L.D. Shu, G.Y. Yang and C.T. Che, J. Nat. Prod., 76, 292 (2013); doi:10.1021/np300727f.