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Chemical Constituents from the Root of Tripterygium wilfordii
Corresponding Author(s) : She-Ban Pu
Asian Journal of Chemistry,
Vol. 26 No. 14 (2014): Vol 26 Issue 14
Abstract
In this paper, the chemical constituents from the root of Tripterygium wilfordii were isolated and characterized. Isolation and purification were carried out on the column chromatography of silica gel and Sephadex LH-20. Fourteen compounds were isolated and identified as (2S,3R,4E,8E,2R)-2-(2'-hydroxyhexadec anoyl) amino-4,8-octadeca diene-1,3-diol (1), soya-cerebrosideI and soya-cerebroside II (2 mixture), adenosine (3), b-sitosterol-palmitate (4) and monopalmitin (5), triptohairic acid (6), hypolide (7), wilforlide B (8), wilforlide A (9), cangoronine (10), salaspermic acid (11), orthosphenic acid (12), 3-hydroxy-2-oxo-3-friedeien- 20-a-carboxylic acid (13), 3b-22a-dihydroxyolean-12-en-29-oic acid (14).
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- A.M. Brinker, J. Ma, P.E. Lipsky and I. Raskin, Photochemistry, 68, 732 (2007); doi:10.1016/j.phytochem.2006.11.029.
- K. Mori and T. Kinsho, Liebigs Ann. Chem., 1988, 807 (1988); doi:10.1002/jlac.198819880818.
- J.L. Lou, L.L. He and L.Y. Kong, Chin. J. Nat. Med., 4, 382 (2006).
- S.L. Yang and X.K. Liu, Chin. J. Nat. Med., 1, 196 (2003).
- B. Wu, Y.P. Ma, J.Z. Yuan and Q.S. Sun, J. Shenyang Pharm. Univ., 27, 116 (2010).
- Y. Sun, A.L. Lu, L. Wei and Y.H. Pei, Chin. J. Med. Chem., 2, 135 (2008).
- K. Nakano, C. Yoshida, W. Furukawa, Y. Takaishi and K. Shishido, Phytochemistry, 49, 1821 (1998); doi:10.1016/S0031-9422(98)00300-8.
- D.G. Wu, X.C. Sun and F. Li, Acta Botanica Yunnannica, 1, 29 (1979).
- L. Ding, Z.X. Zhang, J. Xu and H.X. Zhang, J. Plant Res. Environ., 1, 50 (1992).
- F.J. Guo, P.F. Fang and Y.C. Li, Acta Pharmacol. Sin., 34, 210 (1999).
- J.H. Sheng and B.N. Zhou, Acta Bot. Sin., 36, 475 (1992).
- K.W. Wang, X.L. Hu, L.Q. Sheng and Y.J. Pan, China J. Chin. Mater. Med., 32, 1539 (2007).
- S.L. Mao, S.M. Sang, A.N. Lao and Z.L. Cheng, Chin. Tradit. Herbal Drugs, 31, 729 (2000).
- J.P. Kutney, G.M. Hewitt, G. Lee, K. Piotrowska, M. Roberts and S.J. Rettig, Can. J. Chem., 70, 1455 (1992); doi:10.1139/v92-182.
References
A.M. Brinker, J. Ma, P.E. Lipsky and I. Raskin, Photochemistry, 68, 732 (2007); doi:10.1016/j.phytochem.2006.11.029.
K. Mori and T. Kinsho, Liebigs Ann. Chem., 1988, 807 (1988); doi:10.1002/jlac.198819880818.
J.L. Lou, L.L. He and L.Y. Kong, Chin. J. Nat. Med., 4, 382 (2006).
S.L. Yang and X.K. Liu, Chin. J. Nat. Med., 1, 196 (2003).
B. Wu, Y.P. Ma, J.Z. Yuan and Q.S. Sun, J. Shenyang Pharm. Univ., 27, 116 (2010).
Y. Sun, A.L. Lu, L. Wei and Y.H. Pei, Chin. J. Med. Chem., 2, 135 (2008).
K. Nakano, C. Yoshida, W. Furukawa, Y. Takaishi and K. Shishido, Phytochemistry, 49, 1821 (1998); doi:10.1016/S0031-9422(98)00300-8.
D.G. Wu, X.C. Sun and F. Li, Acta Botanica Yunnannica, 1, 29 (1979).
L. Ding, Z.X. Zhang, J. Xu and H.X. Zhang, J. Plant Res. Environ., 1, 50 (1992).
F.J. Guo, P.F. Fang and Y.C. Li, Acta Pharmacol. Sin., 34, 210 (1999).
J.H. Sheng and B.N. Zhou, Acta Bot. Sin., 36, 475 (1992).
K.W. Wang, X.L. Hu, L.Q. Sheng and Y.J. Pan, China J. Chin. Mater. Med., 32, 1539 (2007).
S.L. Mao, S.M. Sang, A.N. Lao and Z.L. Cheng, Chin. Tradit. Herbal Drugs, 31, 729 (2000).
J.P. Kutney, G.M. Hewitt, G. Lee, K. Piotrowska, M. Roberts and S.J. Rettig, Can. J. Chem., 70, 1455 (1992); doi:10.1139/v92-182.