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Anti-Radiation Damage Performance of Fullerene Ethanolamine
Corresponding Author(s) : Zhi-Jing Zhong
Asian Journal of Chemistry,
Vol. 26 No. 14 (2014): Vol 26 Issue 14
Abstract
Water soluble fullerene ethanolamine derivative was synthesized by adding fullerene (C60) into the ethanolamine under nitrogen atmosphere protection. Its molecular structure was characterized by FTIR and ESI-MS. Hydroxyl radicals were generated by adding ethanol solution and nitronyl nitroxide radicals were generated by adding 4-hydroxy-2,2,6,6-tetramethyl piperidine solution. With irradiation of g-ray, scavenging radicals efficiency of fullerene ethanolamine derivative reached to 49.2 %; with irradiation of fast neutron, fullerene ethanolamine derivative showed excellent scavenging radicals efficiency compared with other materials in experiments, which was decreased first and then increased and attained 65 % at most. The results reveal that no matter irradiation by g-rays or high-energy neutrons, fullerene ethanolamine derivative presentes favorable scavenging radicals efficiency and may be used as a affective protectant for two irradiations.
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- A.C. Cheng, J.L. Hogan and M.A. Caffrey, J. Mol. Biol., 229, 291 (1993); doi:10.1006/jmbi.1993.1034.
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- R. Taylor and D.R.M. Walton, Nature, 363, 685 (1993); doi:10.1038/363685a0.
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References
A.C. Cheng, J.L. Hogan and M.A. Caffrey, J. Mol. Biol., 229, 291 (1993); doi:10.1006/jmbi.1993.1034.
D. Harman, in ed.: W. A. Pryor, Free radical in Biology, Academic Press, New York, vol. 5, p. 255 (1982).
C.N. McEwen, R.G. McKay and B.S. Larsen, J. Am. Chem. Soc., 114, 4412 (1992); doi:10.1021/ja00037a064.
M. Brettreich and A. Hirsch, Tetrahedron Lett., 39, 2731 (1998); doi:10.1016/S0040-4039(98)00491-2.
R. Taylor and D.R.M. Walton, Nature, 363, 685 (1993); doi:10.1038/363685a0.
I.S. Ayene, C.J. Koch and R.E. Krisch, Radiat. Res., 146, 501 (1996); doi:10.2307/3579550.
T. Da Ros and M. Prato, Chem. Commum., 663 (1999); doi:10.1039/A809495K.
F. Wudl, A. Hirsch, K.C. Khemani, T. Suzuki, P.-M. Allemand, A. Koch, H. Eckert, G. Srdanov and H.M. Webb, Survey of Chemical Reactivity of C60, Electrophile and Dieno-Polarophile Par Excellence, ACS Symp. Series, pp. 161-175 (1992).
R. Seshadri, A. Govindaraj, R. Nagarajan, T. Pradeep and C.N.R. Rao, Tetrahedron Lett., 33, 2069 (1992); doi:10.1016/0040-4039(92)88144-T.
M.H.L. Green, J.E. Lowe, A.P.W. Waugh, K.E. Aldridge, J. Cole and C.F. Arlett, Mutat. Res., 316, 91 (1994); doi:10.1016/0921-8734(94)90011-6.