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Identification and Exploration of Lecithin from Novel Sources and its Applications
Corresponding Author(s) : B.N. Vedha Hari
Asian Journal of Chemistry,
Vol. 26 No. 12 (2014): Vol 26 Issue 12
Abstract
Recent research on natural sources such as plants, microbes and other naturally derived compounds have grabbed much attention because of their reduced side effects in treating various ailments and biocompatibility. Technological advancements in the field of medicine have additionally triggered the researchers in developing novel systems for the treatment of many diseases among which cancer research has gained much importance in recent years. Lecithin, a naturally occurring compound present in egg yolk, soya bean oil and milk possess significant anticancer and antioxidant activity. It is composed of phospholipids, fatty acids, carbohydrates and a major constituent of phosphatidylcholine molecule, which is responsible for the normal functioning of nerve cells and cell membranes. The objective of the present work is to extract lecithin compound from Quail’s egg using chemical extraction and its characterization using thin layer chromatography, gas chromatography-mass spectroscopy and nuclear magnetic resonance spectroscopy for the structural elucidation of various constituents present in the crude lecithin. Further, the extracted crude lecithin has been assayed for cytotoxic activity in normal cell line using MTT assay.
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- http://agritech.tnau.ac.in/farm_enterprises/Farm enterprises quil farming.
- T. Sreedevi and J. Joseph, Rasayan J. Chem., 5, 414 (2012).
- L.E. Palacios and T. Wang, J. Am. Oil Chem. Soc., 82, 565 (2005); doi:10.1007/s11746-005-1110-5.
- H. Aro, E.P. Järvenpää, K. Könkö, M. Sihvonen, V. Hietaniemi and R. Huopalahti, Eur. Food Res. Technol., 228, 857 (2009); doi:10.1007/s00217-008-0998-4.
- W. Gładkowski, A. Chojnacka, G. Kiełbowicz, T. Trziszka and C. Wawrzeńczyk, J. Am. Oil Chem. Soc., 89, 179 (2012); doi:10.1007/s11746-011-1893-x.
- C.C. Shah, J. Akoh, R.T. Toledo and M. Corredig, Supercrit. Fluids, 30, 303 (2004); doi:10.1016/j.supflu.2003.09.010.
- B.K. Dwivedi, S. Kumar, C. Nayak and B.K. Mehta, J. Med. Plant. Res., 4, 2252 (2010).
- V.V. Patil, R.V. Galge and B.N. Thorat, Sep. Purif. Technol., 75, 138 (2010); doi:10.1016/j.seppur.2010.08.006.
- A.K. Groen, B.G. Goldhoorn and P.H. Egbers, R.A. Chamuleau, G.N. Tytgat and W.M. Bovée, J. Lipid Res., 31, 1315 (1990).
- Astm E 2161-08 Standard Terminology Relating To Performance Validation In Thermal Analysis.
- A.K. Singh and R. Pannerselvam, Int. J. Pharm. Biomed. Res., 1, 35 (2010).
- Z. He, J. Mao, C.W. Honeycutt, T. Ohno, J.F. Hunt and B.J. Cade-Menun, Biol. Fertil. Soils, 45, 609 (2009); doi:10.1007/s00374-009-0369-8.
- S.F. Ibrahim, E.S. El-Amoudy and K.E. Shady, Int. J. Chem., 3, 40 (2011).
- R. Abbasalipo, A. Salehzadeh and R. Abdullah, Biotechnology, 10, 528 (2011); doi:10.3923/biotech.2011.528.533.
- T. Sreedevi, PG Thesis, Evaluation of Compatibility and Suitability of Emu Egg Lecithin as a Carrier for Topical Delivery: Organogel, SASTRA University, Thanjavur, Tamil Nadu, India (2012).
References
http://agritech.tnau.ac.in/farm_enterprises/Farm enterprises quil farming.
T. Sreedevi and J. Joseph, Rasayan J. Chem., 5, 414 (2012).
L.E. Palacios and T. Wang, J. Am. Oil Chem. Soc., 82, 565 (2005); doi:10.1007/s11746-005-1110-5.
H. Aro, E.P. Järvenpää, K. Könkö, M. Sihvonen, V. Hietaniemi and R. Huopalahti, Eur. Food Res. Technol., 228, 857 (2009); doi:10.1007/s00217-008-0998-4.
W. Gładkowski, A. Chojnacka, G. Kiełbowicz, T. Trziszka and C. Wawrzeńczyk, J. Am. Oil Chem. Soc., 89, 179 (2012); doi:10.1007/s11746-011-1893-x.
C.C. Shah, J. Akoh, R.T. Toledo and M. Corredig, Supercrit. Fluids, 30, 303 (2004); doi:10.1016/j.supflu.2003.09.010.
B.K. Dwivedi, S. Kumar, C. Nayak and B.K. Mehta, J. Med. Plant. Res., 4, 2252 (2010).
V.V. Patil, R.V. Galge and B.N. Thorat, Sep. Purif. Technol., 75, 138 (2010); doi:10.1016/j.seppur.2010.08.006.
A.K. Groen, B.G. Goldhoorn and P.H. Egbers, R.A. Chamuleau, G.N. Tytgat and W.M. Bovée, J. Lipid Res., 31, 1315 (1990).
Astm E 2161-08 Standard Terminology Relating To Performance Validation In Thermal Analysis.
A.K. Singh and R. Pannerselvam, Int. J. Pharm. Biomed. Res., 1, 35 (2010).
Z. He, J. Mao, C.W. Honeycutt, T. Ohno, J.F. Hunt and B.J. Cade-Menun, Biol. Fertil. Soils, 45, 609 (2009); doi:10.1007/s00374-009-0369-8.
S.F. Ibrahim, E.S. El-Amoudy and K.E. Shady, Int. J. Chem., 3, 40 (2011).
R. Abbasalipo, A. Salehzadeh and R. Abdullah, Biotechnology, 10, 528 (2011); doi:10.3923/biotech.2011.528.533.
T. Sreedevi, PG Thesis, Evaluation of Compatibility and Suitability of Emu Egg Lecithin as a Carrier for Topical Delivery: Organogel, SASTRA University, Thanjavur, Tamil Nadu, India (2012).