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Studies on Analgesic and Antiinflammatory Efficacy of Abutilon indicum: A Traditional Drug
Corresponding Author(s) : R. Venkatakrishnan
Asian Journal of Chemistry,
Vol. 26 No. 12 (2014): Vol 26 Issue 12
Abstract
The analgesic and antiinflammatory properties and key chemical constituent from the plant Abutilon indicum which is widely used in traditional folk medicine is presented and discussed in the present paper. The analgesic and antiinflammatory potential of plant extracts of Abutilon indicum was evaluated scientifically. The analgesic activity was screened by tail immersion method and acetic acid induced writhing method. The antiinflammatory activity was evaluated by formalin induced paw edema method and cotton pellet granuloma method. The antiinflammatory and analgesic potential of methanol extracts were tested at a dose level of 100, 200 and 400 mg/kg body wt. The free radical scavenging activity of the selected plant is also established in chromium induced free radical rat models.
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- S.N. Yoganarasimhan, Medicinal Plants of India, vol. 2, p. 10 (2000).
- R.N. Chopra, S.L. Nayar and I.C. Chopra, Glossary of Indian Medicinal Plants, National Institute of Science communication, Council of Scientific and Industrial Research, New Delhi, India (1999).
- The Wealth of India, A Dictionary of Indian Raw Materials and Industrial Products, Council of Scientific and Industrial Research, New Delhi, Vol. 1, p. 21 (1985).
- K.R. Kirtikar and B.D. Basu, Indian Medicinal Plants, Vol II, Central Institute of Medicinal and Aromatic Plants, Lucknow (1992).
- J.B. Harbone, Phytochemical Methods: A Guide to Modern Techniques of plant Analysis, Chapman and Hall, New York, edn. 2, p.85 (1984).
- A. Husain, O.P. Viramani and S.P. Popli, Dictionary of Indian Medicinal Plants, CIMAP, Lucknow, vol. 3 (1992).
- Trease and Evans, Pharmacognosy, ELBS Publication, Delhi, edn. 14, p.498 (1989).
- I.L. Finar, Organic chemistry‐ stereochemistry and the chemistry of natural products 5th ed. Singapore: Pearson Education Ltd; p. 518 (1975).
- H. Plaisted, Philip Contributions from Boyee Thompron Institute, Vol IX, pp. 231-244 (1958).
- C.K. Kokate, A.R. Purohirt and C.B. Gokhale, Pharmacognosy, Nirali Prakashan, edn 27, p. 344 (2004).
- M. N. Ghosh, Fundamentals of Experimental Pharmacology, Scientific Book Agency, Kolkatta, edn 2, p. 155 (1984).
- C.A. Winter an C.C. Porter, J. Am. Pharm. Assoc. Sci. Educ., 46, 515 (1957).
- R. Koster, M. Anderson, and J. De Beer, Acetic acid for analgesic screening, Federation Proceedings, vol. 18, pp. 412-417 (1959).
- S. Aydin, T. Demir, Y. Ozturk and K.H.C. Baser, Phytother. Res., 13, 20 (1999); doi:10.1002/(SICI)1099-1573(199902)13:1<20::AID-PTR380>3.0.CO;2-J.
References
S.N. Yoganarasimhan, Medicinal Plants of India, vol. 2, p. 10 (2000).
R.N. Chopra, S.L. Nayar and I.C. Chopra, Glossary of Indian Medicinal Plants, National Institute of Science communication, Council of Scientific and Industrial Research, New Delhi, India (1999).
The Wealth of India, A Dictionary of Indian Raw Materials and Industrial Products, Council of Scientific and Industrial Research, New Delhi, Vol. 1, p. 21 (1985).
K.R. Kirtikar and B.D. Basu, Indian Medicinal Plants, Vol II, Central Institute of Medicinal and Aromatic Plants, Lucknow (1992).
J.B. Harbone, Phytochemical Methods: A Guide to Modern Techniques of plant Analysis, Chapman and Hall, New York, edn. 2, p.85 (1984).
A. Husain, O.P. Viramani and S.P. Popli, Dictionary of Indian Medicinal Plants, CIMAP, Lucknow, vol. 3 (1992).
Trease and Evans, Pharmacognosy, ELBS Publication, Delhi, edn. 14, p.498 (1989).
I.L. Finar, Organic chemistry‐ stereochemistry and the chemistry of natural products 5th ed. Singapore: Pearson Education Ltd; p. 518 (1975).
H. Plaisted, Philip Contributions from Boyee Thompron Institute, Vol IX, pp. 231-244 (1958).
C.K. Kokate, A.R. Purohirt and C.B. Gokhale, Pharmacognosy, Nirali Prakashan, edn 27, p. 344 (2004).
M. N. Ghosh, Fundamentals of Experimental Pharmacology, Scientific Book Agency, Kolkatta, edn 2, p. 155 (1984).
C.A. Winter an C.C. Porter, J. Am. Pharm. Assoc. Sci. Educ., 46, 515 (1957).
R. Koster, M. Anderson, and J. De Beer, Acetic acid for analgesic screening, Federation Proceedings, vol. 18, pp. 412-417 (1959).
S. Aydin, T. Demir, Y. Ozturk and K.H.C. Baser, Phytother. Res., 13, 20 (1999); doi:10.1002/(SICI)1099-1573(199902)13:1<20::AID-PTR380>3.0.CO;2-J.