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Content Analysis of Flavonoids in the Stems and Roots of Acanthopanax Species in Different Countries
Corresponding Author(s) : Sanghyun Lee
Asian Journal of Chemistry,
Vol. 26 No. 12 (2014): Vol 26 Issue 12
Abstract
Content analysis of flavonoids in the stems and roots of Acanthopanax species (A. divaricatus, A. koreanum, A. senticosus and A. sessiliflorus) in different nations was conducted by high performance liquid chromatography. In the stems and roots of Acanthopanax species, the contents of rutin, hyperin, afzelin, quercetin and kaempferol were 0.024-0.326 and 0.059-0.531, 0.391-4.256 and 0.957-3.517, 0.935-10.572 and 1.019-1.185, 0.375-0.885 and 0.394-0.501, 0.193-0.872 and 0.179-0.500 mg/g, respectively. Total content of flavonoids in the stems and roots was highest in A. senticosus (Mt. Baekdu) and A. sessiliflorus (Gongju), respectively. Also, hyperin and afzelin were the most abundant compounds in the roots and stems of Acanthopanax species, respectively. This result will provide useful information in the application of these flavonoids from Acanthopanax species in the nutraceutical, pharmaceutical and cosmeceutical areas.
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References
D.D. Soejarto and N.R. Farnsworth, Bot. Mus. Lealf. Harv. Univ., 26, 339 (1978).
C.S. Yook, Coloured Medicinal Plants of Korea. Academy Book Co., Seoul, Korea. p. 377 (1990).
M.K. Huh, H.W. Huh and J.S. Choi, J. Korean Soc. Hort. Sci., 46, 225 (2005).
N. Ni and X.Q. Liu, Chin. Tradit. Herbal Drugs, 37, 1895 (2006).
C. Tohda, M. Ichimura, Y.J. Bai, K. Tanaka, S. Zhu and K. Komatsu, J. Pharmacol. Sci., 107, 329 (2008); doi:10.1254/jphs.08046FP.
B.T. Gaffney, H.M. Hügel and P.A. Rich, Med. Hypotheses, 56, 567 (2001); doi:10.1054/mehy.2000.1163.
M. Yasue, Y. Kato, Y.M. Lin and J. Sakakibara, Yakugaku Zasshi, 88, 738 (1968).
J. Kitajima, Y. Takamori and Y. Tanaka, Yakugaku Zasshi, 109, 188 (1989).
J.Y. Chung and D.R. Hanh, Yakhak Hoeji, 35, 240 (1991).
K. Shirasuna, M. Miyakoshi, S. Mimoto, S. Isoda, Y. Satoh, Y. Hirai, Y. Ida and J. Shoji, Phytochemistry, 45, 579 (1997); doi:10.1016/S0031-9422(97)00017-4.
S. Lee, B.K. Kim, S.H. Cho and K.H. Shin, Arch. Pharm. Res., 25, 280 (2002); doi:10.1007/BF02976626.
M. Bekker, R. Bekker and V.E. Brandt, Phytochemistry, 67, 818 (2006); doi:10.1016/j.phytochem.2006.01.015.
K.H. Shin and S. Lee, Nat. Prod. Sci., 8, 111 (2002).
Q. An, C.J. Yang, Y. Song, K. Yu, Z.L. Xiong and F.M. Li, Nat. Prod. Res. Dev., 20, 765 (2008).
E.-J. Lee, Y.-S. Jang and K.-Y. Paek, Korean J. Hort. Sci. Technol., 29, 189 (2011).
H.Y. Kim, D.G. Lee, K.H. Lee and S. Lee, Hort. Environ. Biotechnol., 53, 242 (2012); doi:10.1007/s13580-012-0030-6.
S.-Y. Mok, J.M. Lee, H.M. Kim, D.G. Lee, Y.-H. Yoon, E.J. Cho and S. Lee, Nat. Prod. Sci., 17, 230 (2011).
S. Lee, H.S. Park, Y. Notsu, H.S. Ban, Y.P. Kim, K. Ishihara, N. Hirasawa, S.H. Jung, Y.S. Lee, S.S. Lim, E.H. Park, K.H. Shin, T. Seyama, J. Hong and K. Ohuchi, Phytother. Res., 22, 1552 (2008); doi:10.1002/ptr.2529.
S.-Y. Mok and S. Lee, Food Chem., 136, 969 (2013); doi:10.1016/j.foodchem.2012.08.091.
J.M. Lee, D.G. Lee, K.H. Lee, S.H. Cho, C.G. Park and S. Lee, Nat. Prod. Sci., 19, 15 (2013).
Y.J. Jeong, Y.J. Choi, H.M. Kwon, S.W. Kang, H.S. Park, M. Lee and Y.H. Kang, Br. J. Nutr., 93, 581 (2005); doi:10.1079/BJN20041397.
M.A. Alsaif, Pak. J. Nutr., 8, 745 (2009); doi:10.3923/pjn.2009.745.754.
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E. Middleton Jr., C. Kandaswami and T.C. Theoharides, Pharmacol. Rev., 52, 673 (2000).
J. Bernatoniene, S. Trumbeckaite, D. Majiene, R. Baniene, G. Baliutyte, A. Savickas and A. Toleikis, Phytother. Res., 23, 1701 (2009); doi:10.1002/ptr.2815.
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Y.B. Yu, H. Miyashiro, N. Nakamura, M. Hattori and J.C. Park, Arch. Pharm. Res., 30, 820 (2007); doi:10.1007/BF02978831.
A. Murakami, H. Ashida and J. Terao, Cancer Lett., 269, 315 (2008); doi:10.1016/j.canlet.2008.03.046.
M.R. Hyun, Y.S. Lee and Y.H. Park, Korean J. Hort. Sci. Technol., 29, 68 (2011).
J.M. Calderon-Montano, E. Burgos-Moron, C. Perez-Guerrero and M. Lopez-Lazaro, Mini Rev. Med. Chem., 11, 298 (2011); doi:10.2174/138955711795305335.