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Vol. 26 No. 11 (2014): Vol 26 Issue 11

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Chemical Constituents of n-Butanol Extract of Capparis spinosa L.

https://doi.org/10.14233/ajchem.2014.17544
Wen-Lan Li
Institute of Materia Medica and Postdoctoral Programme of Harbin University of Commerce, Harbin, P.R. China
Lei Yu
Engineering Research Center of Natural Anticancer Drugs, Ministry of Education, Harbin, P.R. China
Yu-Bin Ji
Institute of Materia Medica and Postdoctoral Programme of Harbin University of Commerce, Harbin, P.R. China

Corresponding Author(s) : Lei Yu

yulei912@163.com

Asian Journal of Chemistry, Vol. 26 No. 11 (2014): Vol 26 Issue 11

Abstract

The aim of this study was to ascertain chemical constituents of n-butanol extract of Capparis spinosa L. fruits. The n-butanol extract of Capparis spinosa L. was effective at controlling S180 tumour growth in a murine model. Silica gel column chromatography, Sephadex LH-20 and re-crystallization methods were used to isolate and purify the n-butanol extract. Chemical structures were elucidated by spectroscopic analyses and compared with literature. As results, nine known compounds were isolated and identified as: bis-(5-fomylfurfuryl) ether (1), 5-(hydroxymethyl)furfural (2), uracil (3), adenosine (4), 2-hydroxy-6-methoxy-1H-indol-3-ethanone (5), rutin (6), 2-methyl-6-(1',2',3',4'-tetrahydroxybutyl)pyrazine (7), p-hydroxy-benzoic acid (8) and stachydrine (9). There in, the compound 7 was identified in Capparis spinosa L. for the first time.

Keywords

Capparis spinosa L. n-Butanol extract Antitumor activity Chemical constituents Spectroscopic analyses
Li, W.-L., Yu, L., & Ji, Y.-B. (2014). Chemical Constituents of n-Butanol Extract of Capparis spinosa L. Asian Journal of Chemistry, 26(11), 3435–3437. https://doi.org/10.14233/ajchem.2014.17544
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