Phytochemical, Antibacterial and Antifungal Activities of Alkaloids Extracted from Peganum harmala (Linn.) Seeds of South of Algeria

N. Behidj-Benyounes; T. Dahmene; N. Allouche; A. Laddad

doi:10.14233/ajchem.2014.16138

Issue

Vol. 26 No. 10 (2014): Vol 26 Issue 10

Issue Published : May 10, 2014

This work is licensed under a Creative Commons Attribution 4.0 International License.

Phytochemical, Antibacterial and Antifungal Activities of Alkaloids Extracted from Peganum harmala (Linn.) Seeds of South of Algeria

https://doi.org/10.14233/ajchem.2014.16138

N. Behidj-Benyounes

Laboratory of Soft Technologies, Valorisation, Physico-chemistry of Biological Material and Biodiversity, Faculty of Sciences, University M'Hamed Bougara of Boumerdes, Boumerdes 35000 Algeria

T. Dahmene

Laboratory of Soft Technologies, Valorisation, Physico-chemistry of Biological Material and Biodiversity, Faculty of Sciences, University M'Hamed Bougara of Boumerdes, Boumerdes 35000 Algeria

N. Allouche

Laboratory of Soft Technologies, Valorisation, Physico-chemistry of Biological Material and Biodiversity, Faculty of Sciences, University M'Hamed Bougara of Boumerdes, Boumerdes 35000 Algeria

A. Laddad

Laboratory of Soft Technologies, Valorisation, Physico-chemistry of Biological Material and Biodiversity, Faculty of Sciences, University M'Hamed Bougara of Boumerdes, Boumerdes 35000 Algeria

Asian Journal of Chemistry, Vol. 26 No. 10 (2014): Vol 26 Issue 10
Article Published : May 10, 2014

Abstract

This work reports the phytochemical screening of the plant extracts recovered from the seeds of Peganum harmala L. (Zygophyllaceae). Preliminary phytochemical analysis of plants extracts showed the presence of alkaloids, coumarins, saponins, quinones and flavonoids free. These natural substances are recovered by different solvents (aqueous, ethanolic and hexane). Thus evaluation of the antimicrobial activity has only touched the alkaloids. The antimicrobial effect of alkaloids is evaluated on several microorganisms. It should be noted that these agents are characterized by a high frequency of contamination and pathogenicity. It is noted that Staphylococcus aureus, Saccharomyces cerievisae and E. coli are very sensitive in respect of the ethanol extract. Pseudomonas aerogenosa and Penicillium sp. are resistant to this extract. The other microorganisms are moderately sensitive. The study of the antimicrobial activity of different extracts of the seeds of Peganum harmala L. showed an optimal activity with the ethanol extract.

Keywords

Peganum harmala Seeds Alkaloids Antimicrobial activity

Behidj-Benyounes, N., Dahmene, T., Allouche, N., & Laddad, A. (2014). Phytochemical, Antibacterial and Antifungal Activities of Alkaloids Extracted from Peganum harmala (Linn.) Seeds of South of Algeria. Asian Journal of Chemistry, 26(10), 2960–2964. https://doi.org/10.14233/ajchem.2014.16138

Download Citation

References

J.-C. Roland, Des plantes et des hommes, Vinbert Press, Paris, p. 163 (2002).
A. Lhuillier, Ph.D. Thesis, Contribution à l'étude phytochimique de quatre plantes malgoches: Agauria salicifolia, Hook.f ex Olivier Agauria polyphylla, Baker (Ericaceae), Tambourissa trichophylla Baker (Monimiaceae) et Ombelia concinna Baker (Myrinaceae), Toulouse, France, p. 98 (2007).
P. Delaveau, Histoire et renouveau des plantes médicinales, Albin Michel Press, Paris, p. 5 (1982).
O. Catier and D. Roux, Botanique pharmacognosie phytothérapie, Wolters Kluwer Collection Porphyre Press, France, pp. 89-90 (2007).
K. Sekkoum, A. Cheriti and S. Taleb, Asian J. Chem., 22, 2891 (2010).
A. Hallimi, Les plantes médicinales en Algérie, Berti Press Algérie, p. 42 (2004).
Q.A. El-Dwairi, Asian J. Chem., 19, 3887 (2007).
P. Iserin, Encyclopédie des plantes médicinales, Larousse Press, France, p. 335 (2001).
I.E. Leger, Debaene Press, France, vol. 2, pp. 360-860 (1989).
G. Sacchetti, S. Maietti, M. Muzzoli, M. Scaglianti, S. Manfredini, M. Radice and R. Bruni, Food Chem., 91, 621 (2005); doi:10.1016/j.foodchem.2004.06.031.
O.Y. Celiktas, E.E.H. Kocabas, E. Bedir, F.V. Sukan, T. Ozek and K.H.C. Baser, Food Chem., 100, 553 (2007); doi:10.1016/j.foodchem.2005.10.011.
J.L. Fauchere and J.L. Avril Albin, Ellipses Press, Paris, p. 365 (2002).
C. Munir, M.I. Zaidi, A. Nasir, U. Atta and N. Ahmad, Fitoterapia, 66, 73 (1995).
M. Kartal, M.L. Altun and S. Kurucu, J. Pharm. Biomed. Anal., 31, 263 (2003); doi:10.1016/S0731-7085(02)00568-X.
M.K. Han, S.I. Kim and Y.J. Ahn, J. Stored Prod. Res., 42, 15 (2006); doi:10.1016/j.jspr.2004.11.002.
L.M. Idrissi Hassani and M. El Hadek, Acta Bot. Gallica, 146, 353 (1999); doi:10.1080/12538078.1999.10515822.
L. Claude, Contribution à l’étude de Peganum harmala L., Thèse de pharmacie, France, p. 335 (1967).
N. El Allagui, M. Bourijate and S. Tahrouch, Congrès International de Biochimie, Aghadir, pp. 360-357 (2006).
A. R. Shahverdi, Monsef-Esfahani H R, Nickavar B, Bitarafan L, Khodaee S, Khoshakhlagh, Z. Naturforsch., 60C, 707 (2005).
M. R. Boukef, Les plantes dans la médicine traditionnelle tunisienne. A.C.C.T. Press, Paris, p. 350 (1986).
M.C. Pibiri, Assainissement microbiologique de l’air et du système de ventilation au moyen d’huile essentielle, Thèse de Doctorat, Ecole polytechnique fédérale, Lausanne, p. 177 (2006).
C.W. Balentine, P.G. Crandall, C.A. O’bryan, D.Q. Duong and F.W. Pohlman, Meat Sci., 73, 413 (2006); doi:10.1016/j.meatsci.2005.12.003.
S. Cosentino, C.I.G. Tuberoso, B. Pisano, M. Satta, V. Mascia, E. Arzedi and F. Palmas, Lett. Appl. Microbiol., 29, 130 (1999); doi:10.1046/j.1472-765X.1999.00605.x.
G. Debillerbeck, Activité antifongique de l’huile essentielle de Cymbopogon nardus sur Aspergillus niger. Evaluation d’un bioréacteur pour l’Etude de l’effet inhibiteur des substances volatiles en phase vapeur, Thèse de doctorat, Faculté des sciences pharmaceutiques. Institut national polytechnique Toulouse, p. 236 (2000).
M. Marino, C. Bersani and G. Comi, J. Food Prot., 62, 1023 (1999).
R.N. Yadava and V. Verma, Asian J. Chem., 15, 842 (2003).
S.C. Chao, D.G. Young and C.J. Oberg, J. Essent. Oils Res., 12, 639 (2000); doi:10.1080/10412905.2000.9712177.
M. El Gayyar, F.A. Graughon, D.A. Golden and J.R. Mount, J. Food Prot., 64, 1019 (2001).
P.J. Delaquis, K. Tanish, B. Girard and G. Mazza, Int. J. Food Microbiol., 74, 101 (2002); doi:10.1016/S0168-1605(01)00734-6.
L. Iauk, R. Costanzo, F. Caccamo, A. Rapisarda, R. Musumeci, I. Milazzo and G. Blandino, Fitoterapia, 78, 159 (2007); doi:10.1016/j.fitote.2006.10.007.
G. Nenaah, Fitoterapia, 81, 779 (2010); doi:10.1016/j.fitote.2010.04.004.
H.R. Monsef, A. Ghobadi, M. Iranshahi and M. Abdollahi, J. Pharm. Pharmaceut. Sci., 7, 65 (2004).
M. Mahmoudian, H. Jalipour and P. Salehian, Iran. J. Pharmacol. Therap., 1, 1 (2002).
J.S. Glasby, Encyclopedia of the alkaloids, Plenum Press, France, pp. 58-61 (1978).
S.K. Gupta, P.K. Sharma and S.H. Ansari, Asian J. Chem., 17, 1355 (2005).
D. Basaran, H. Nurcihan, S. G. Beyza and G.F. Gucin, Asian J. Chem., 22, 6321 (2010).

References

J.-C. Roland, Des plantes et des hommes, Vinbert Press, Paris, p. 163 (2002).

A. Lhuillier, Ph.D. Thesis, Contribution à l'étude phytochimique de quatre plantes malgoches: Agauria salicifolia, Hook.f ex Olivier Agauria polyphylla, Baker (Ericaceae), Tambourissa trichophylla Baker (Monimiaceae) et Ombelia concinna Baker (Myrinaceae), Toulouse, France, p. 98 (2007).

P. Delaveau, Histoire et renouveau des plantes médicinales, Albin Michel Press, Paris, p. 5 (1982).

O. Catier and D. Roux, Botanique pharmacognosie phytothérapie, Wolters Kluwer Collection Porphyre Press, France, pp. 89-90 (2007).

K. Sekkoum, A. Cheriti and S. Taleb, Asian J. Chem., 22, 2891 (2010).

A. Hallimi, Les plantes médicinales en Algérie, Berti Press Algérie, p. 42 (2004).

Q.A. El-Dwairi, Asian J. Chem., 19, 3887 (2007).

P. Iserin, Encyclopédie des plantes médicinales, Larousse Press, France, p. 335 (2001).

I.E. Leger, Debaene Press, France, vol. 2, pp. 360-860 (1989).

G. Sacchetti, S. Maietti, M. Muzzoli, M. Scaglianti, S. Manfredini, M. Radice and R. Bruni, Food Chem., 91, 621 (2005); doi:10.1016/j.foodchem.2004.06.031.

O.Y. Celiktas, E.E.H. Kocabas, E. Bedir, F.V. Sukan, T. Ozek and K.H.C. Baser, Food Chem., 100, 553 (2007); doi:10.1016/j.foodchem.2005.10.011.

J.L. Fauchere and J.L. Avril Albin, Ellipses Press, Paris, p. 365 (2002).

C. Munir, M.I. Zaidi, A. Nasir, U. Atta and N. Ahmad, Fitoterapia, 66, 73 (1995).

M. Kartal, M.L. Altun and S. Kurucu, J. Pharm. Biomed. Anal., 31, 263 (2003); doi:10.1016/S0731-7085(02)00568-X.

M.K. Han, S.I. Kim and Y.J. Ahn, J. Stored Prod. Res., 42, 15 (2006); doi:10.1016/j.jspr.2004.11.002.

L.M. Idrissi Hassani and M. El Hadek, Acta Bot. Gallica, 146, 353 (1999); doi:10.1080/12538078.1999.10515822.

L. Claude, Contribution à l’étude de Peganum harmala L., Thèse de pharmacie, France, p. 335 (1967).

N. El Allagui, M. Bourijate and S. Tahrouch, Congrès International de Biochimie, Aghadir, pp. 360-357 (2006).

A. R. Shahverdi, Monsef-Esfahani H R, Nickavar B, Bitarafan L, Khodaee S, Khoshakhlagh, Z. Naturforsch., 60C, 707 (2005).

M. R. Boukef, Les plantes dans la médicine traditionnelle tunisienne. A.C.C.T. Press, Paris, p. 350 (1986).

M.C. Pibiri, Assainissement microbiologique de l’air et du système de ventilation au moyen d’huile essentielle, Thèse de Doctorat, Ecole polytechnique fédérale, Lausanne, p. 177 (2006).

C.W. Balentine, P.G. Crandall, C.A. O’bryan, D.Q. Duong and F.W. Pohlman, Meat Sci., 73, 413 (2006); doi:10.1016/j.meatsci.2005.12.003.

S. Cosentino, C.I.G. Tuberoso, B. Pisano, M. Satta, V. Mascia, E. Arzedi and F. Palmas, Lett. Appl. Microbiol., 29, 130 (1999); doi:10.1046/j.1472-765X.1999.00605.x.

G. Debillerbeck, Activité antifongique de l’huile essentielle de Cymbopogon nardus sur Aspergillus niger. Evaluation d’un bioréacteur pour l’Etude de l’effet inhibiteur des substances volatiles en phase vapeur, Thèse de doctorat, Faculté des sciences pharmaceutiques. Institut national polytechnique Toulouse, p. 236 (2000).

M. Marino, C. Bersani and G. Comi, J. Food Prot., 62, 1023 (1999).

R.N. Yadava and V. Verma, Asian J. Chem., 15, 842 (2003).

S.C. Chao, D.G. Young and C.J. Oberg, J. Essent. Oils Res., 12, 639 (2000); doi:10.1080/10412905.2000.9712177.

M. El Gayyar, F.A. Graughon, D.A. Golden and J.R. Mount, J. Food Prot., 64, 1019 (2001).

P.J. Delaquis, K. Tanish, B. Girard and G. Mazza, Int. J. Food Microbiol., 74, 101 (2002); doi:10.1016/S0168-1605(01)00734-6.

L. Iauk, R. Costanzo, F. Caccamo, A. Rapisarda, R. Musumeci, I. Milazzo and G. Blandino, Fitoterapia, 78, 159 (2007); doi:10.1016/j.fitote.2006.10.007.

G. Nenaah, Fitoterapia, 81, 779 (2010); doi:10.1016/j.fitote.2010.04.004.

H.R. Monsef, A. Ghobadi, M. Iranshahi and M. Abdollahi, J. Pharm. Pharmaceut. Sci., 7, 65 (2004).

M. Mahmoudian, H. Jalipour and P. Salehian, Iran. J. Pharmacol. Therap., 1, 1 (2002).

J.S. Glasby, Encyclopedia of the alkaloids, Plenum Press, France, pp. 58-61 (1978).

S.K. Gupta, P.K. Sharma and S.H. Ansari, Asian J. Chem., 17, 1355 (2005).

D. Basaran, H. Nurcihan, S. G. Beyza and G.F. Gucin, Asian J. Chem., 22, 6321 (2010).

Issue

Vol. 26 No. 10 (2014): Vol 26 Issue 10

Phytochemical, Antibacterial and Antifungal Activities of Alkaloids Extracted from Peganum harmala (Linn.) Seeds of South of Algeria

Abstract

Keywords

Full Article

Download Citation

References

Table Of Contents