Copyright (c) 2021 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Chemical Constituents of Suaeda monoica and its Biological Activity
Corresponding Author(s) : Ahmed A.M. Abdelgawad
Asian Journal of Chemistry,
Vol. 33 No. 11 (2021): Vol 33 Issue 11, 2021
Abstract
The ethanolic extract of the aerial parts of Suaeda monoica was successively fractionated using petroleum ether, dichloromethane, ethyl acetate and methanol. The GC-MS analysis of dichloromethane fraction has resulted in the identification of 24 non-polar compounds. N,N-dimethyl-1-dodecanamine (19.13%), methyl (Z)-9-oleate (18.1%) and 2-methoxy-3-(2-propenyl)phenol (12.14%) were the major components and fatty acids methyl esters represented the major class of this nonpolar components. Phytochemical study of the ethyl acetate and methanol fractions led to isolation and identification of seven known compounds identified as pyrogallol, ferulic acid, luteolin, (+)-catechien, gallic acid, naringin and naringenin. Dichloromethane, ethyl aetate and methanol fractions exhibited weak to moderate antioxidant activity using DPPH free radical scavenging method. Ethyl acetate and methanol fractions showed no antifungal activity and weak to good antibacterial activity by diffusion agar technique, while the dichloromethane showed potent activity against all the tested strains. Different fractions revealed weak lipase inhibitory effect.
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- P.D. Kumara, G.L. Jayawardane and A.P. Aluwihare, Ceylon Med. J., 46, 69 (2014); https://doi.org/10.4038/cmj.v46i2.6499
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- F.A. van52 de Laar, Vasc. Health Risk Manag., 4, 1189 (2008); https://doi.org/10.2147/VHRM.S3119
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References
P.D. Kumara, G.L. Jayawardane and A.P. Aluwihare, Ceylon Med. J., 46, 69 (2014); https://doi.org/10.4038/cmj.v46i2.6499
S.K. Chatterjee, I. Bhattacharjee and G. Chandra, Asian Pac. J. Trop. Med., 4, 35 (2011); https://doi.org/10.1016/S1995-7645(11)60028-X
J. Patra, N. Dhal and H. Thatoi, Asian Pac. J. Trop. Med., 4, 727 (2011); https://doi.org/10.1016/S1995-7645(11)60182-X
R. Ksouri, W. Megdiche, H. Falleh, N. Trabelsi, M. Boulaaba, A. Smaoui and C. Abdelly, C. R. Biol., 331, 865 (2008); https://doi.org/10.1016/j.crvi.2008.07.024
L. Boulos, Flora of Egypt, Al-Hadara Publishing, Cairo, pp. 114–115 (1999).
L. Boulos, Kew Bull., 46, 291 (1991); https://doi.org/10.2307/4110599
S. Ravikumar, M. Gnanadesigan, J.S. Serebiah and S.J. Inbaneson, Life Sci. Med. Res., 2, 1 (2010).
S. Ravikumar, M. Gnanadesigan, S.J. Inbaneson and A. Kalaiarasi, Indian J. Exp. Biol., 49, 455 (2011).
J.R.L. Allen, Quat. Sci. Rev., 19, 1155 (2000); https://doi.org/10.1016/S0277-3791(99)00034-7
K. Kubitzki, Eds: J.G. Rohwer and V. Bittrich, The Families and Genera of Vascular Plants, In: Flowering Plants Dicotyledons: Magnoliid, Hamamelid and Caryophyllid Families, Berlin, Heidelberg, Gmbh: Springer, Verlag, vol. 2 (2013).
Y.A. El-Amier, E.S.F. El-Halawany and A.K. Khudhair, Int. J. Nat. Sci. Res., 5, 31 (2017); https://doi.org/10.18488/journal.63.2017.52.31.42
W.M. Bandaranayake, Mangroves Salt Marshes, 2, 133 (1998); https://doi.org/10.1023/A:1009988607044
F.A. Ahmed and T.A. El-Bassossy, Asian J. Pharm. Clin. Res., 13, 40 (2020); https://doi.org/10.22159/ajpcr.2020.v13i3.36503
F.A. Ahmed, A.M.D. El-Mesallamy and T.A.I. El-Bassossy, Acta Pol. Pharm., 76, 653 (2019); https://doi.org/10.32383/appdr/105607
S. El-Desouky, A. Abdelgawad, A. El-Hagrassi, U. Hawas and Y.-K. Kim, Acta Pol. Pharm., 76, 691 (2019); https://doi.org/10.32383/appdr/105158
E.M. Atta, K.H. Hegab, A.A.M. Abdelgawad and A.A. Youssef, Saudi Pharm. J., 27, 584 (2019); https://doi.org/10.1016/j.jsps.2019.02.006
A.M.D. El-Mesallamy, M. El-Gerby, M.H.M.A.E. Azim and A. Awad, J. Essent. Oil-Bear. Plants, 15, 900 (2012); https://doi.org/10.1080/0972060X.2012.10662592
R.P. Adams, Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry, Allured Publishing Corporation, Ed.: 4 (2007).
M.E. Letelier, A. Molina-Berrios, J. Cortés-Troncoso, J. Jara-Sandoval, M. Holst, K. Palma, M. Montoya, D. Miranda and V. González-Lira, J. Toxicol. In Vitro, 22, 279 (2008); https://doi.org/10.1016/j.tiv.2007.08.002
M. Joyeux, A. Lobstein, R. Anton and F. Mortier, Planta Med., 61, 126 (1995); https://doi.org/10.1055/s-2006-958030
C. Viturro, A. Molina and G. Schmeda-Hirschmann, Phytother. Res., 13, 422 (1999); https://doi.org/10.1002/(SICI)1099-1573(199908/09)13:5<422::AIDPTR462>3.0.CO;2-M
CLSI Method for Antifungal Disk Diffusion Susceptibility Testing of Yeasts, Wayne, Pennsylvania, 1898, USA (2004).
CLSI Performance Standards for Antimicrobial Disk Susceptibility Tests, Approved Standard, CLSI document M02-A11, Wayne, Pennsylvania, 19087, USA, Ed.: 7 (2012).
Y.S. Kim, Y.M. Lee, H. Kim, J. Kim, D.K. Jang, J.H. Kim and J.S. Kim, J. Ethnopharmacol., 130, 621 (2010); https://doi.org/10.1016/j.jep.2010.05.053
G. Manoj, S.H. Manohar and H.N. Murthy, Nat. Prod. Res., 26, 2152 (2012); https://doi.org/10.1080/14786419.2011.633082
S. Choudhary, O. Silakari and P.K. Singh, Mini Rev. Med. Chem., 18, 1452 (2018); https://doi.org/10.2174/1389557518666180416150552
M.J. Pagliassotti, E.C. Gayles and J.O. Hill, Ann. N. Y. Acad. Sci., 827, 431 (1997); https://doi.org/10.1111/j.1749-6632.1997.tb51853.x
B.M. Spiegelman and J.S. Flier, Cell, 104, 531 (2001); https://doi.org/10.1016/S0092-8674(01)00240-9
R.S. Padwal and S.R. Majumdar, Lancet, 369, 71 (2007); https://doi.org/10.1016/S0140-6736(07)60033-6
F.A. van52 de Laar, Vasc. Health Risk Manag., 4, 1189 (2008); https://doi.org/10.2147/VHRM.S3119
L.K. Han, Y. Kimura, M. Kawashima, T. Takaku, T. Taniyama, T. Hayashi, Y.N. Zheng and H. Okuda, Int. J. Obes. Relat. Metab. Disord., 25, 1459 (2001); https://doi.org/10.1038/sj.ijo.0801747
L.K. Han, Y.N. Zheng, B.J. Xu, H. Okuda and Y. Kimura, J. Nutr., 132, 2241 (2002); https://doi.org/10.1093/jn/132.8.2241
M. Nakai, Y. Fukui, S. Asami, Y. Toyoda-Ono, T. Iwashita, H. Shibata, T. Mitsunaga, F. Hashimoto and Y. Kiso, J. Agric. Food Chem., 53, 4593 (2005); https://doi.org/10.1021/jf047814+
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