GC-MS Analysis, Phytochemical Screening and Biological Activity of Bauhinia tomentosa (Linn.)

R. Mini; V. Prabhu; K. Vimaladevi; J. Sowmiya; G. Sibi

doi:10.14233/ajchem.2021.23363

Issue

Vol. 33 No. 11 (2021): Vol 33 Issue 11, 2021

Issue Published : October 20, 2021

This work is licensed under a Creative Commons Attribution 4.0 International License.

GC-MS Analysis, Phytochemical Screening and Biological Activity of Bauhinia tomentosa (Linn.)

https://doi.org/10.14233/ajchem.2021.23363

R. Mini

PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India

V. Prabhu

PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India

K. Vimaladevi

PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India

J. Sowmiya

PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India

G. Sibi

Department of Biotechnology, Indian Academy Degree College (Autonomous), Bangalore-560043, India

Corresponding Author(s) : V. Prabhu

prabhunmr@gmail.com

Asian Journal of Chemistry, Vol. 33 No. 11 (2021): Vol 33 Issue 11, 2021
Article Published : October 20, 2021

Abstract

Present study aimed to evaluate the chemical composition and biological activity for methanolic extract of Bauhinia tomentosa (Linn.) leaves grown in Western Ghats region of South India. The preliminary phytochemical screening tests revealed the presence of steroids, alkaloids, terpenoids, flavonoids, glycosides and phenolic compounds in the leaf extract. A total of 19 compounds were identified through gas chromatography-mass spectroscopy (GC-MS) analysis of methanolic extract of B. tomentosa. The major compounds identified were phytol (23.96%), n-hexadecanoic acid (11.62%), squalene (8.85%) and the minor compounds are trans-bis(2-methylpropyl)-4,6-dioxane(0.13%), dihydro-cis-α-copaene-8-ol (0.14%), tetradecanoic acid (0.81%), respectively. Antibacterial activity of the extract showed the zone of inhibition 18 mm at 200 μg/mL against S. aureus, followed by 15 and 16 mm against S. anginosus, K. pneumoniae at 200 μg/mL, respectively. Antioxidant activity of methanolic extract of B. tomentosa leaves showed the maximum IC₅₀ value with 75.07 % of scavenging activity at the concentration of 5 μg/mL.

Keywords

Bauhinia tomentosa GC-MS Antibacterial activity Antioxidant activity

Mini, R., Prabhu, V., Vimaladevi, K., Sowmiya, J., & Sibi, G. (2021). GC-MS Analysis, Phytochemical Screening and Biological Activity of Bauhinia tomentosa (Linn.). Asian Journal of Chemistry, 33(11), 2641–2644. https://doi.org/10.14233/ajchem.2021.23363

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J. Zhang, I.J. Onakpoya, P. Posadzki and M. Eddouks, Evid. Based Compl. Altern. Med., 2015, 316706 (2015); https://doi.org/10.1155/2015/316706

P. Sharma, A.B. Jha, R.S. Dubey and M. Pessarakli, J. Botany, 2012, 217037 (2012); https://doi.org/10.1155/2012/217037

P. Panda, P. Dash and G. Ghosh, Nat. Prod. Res., 32, 596 (2018); https://doi.org/10.1080/14786419.2017.1326487

V.C. Filho, Phytother. Res., 23, 1347 (2009); https://doi.org/10.1002/ptr.2756

I.F. Bonilha, C.H.F. Cuelho, J.C. Brondani, J.F. Cossetin and L.D. Marangoni, Rev. Cubana Farm., 49, 583 (2015).

P. Panda, S.K. Bhuyan, C. Dash and D. Pradhan, Indian J. Nat. Prod. Resour., 11, 169 (2020).

S. Gopalakrishnan and E. Vadivel, Int. J. Pharm. Sci. Drug Res., 8, 149 (2016); https://doi.org/10.25004/IJPSDR.2016.080304

R. Naz, M. Anis and I.M. Aref, J. Hortic. Sci. Biotechnol., 86, 37 (2011); https://doi.org/10.1080/14620316.2011.11512722

S. Solomon, N. Muruganantham and M.M. Senthamilselvi, J. Pharmacogn. Phytochem., 5, 287 (2016).

E.N. Quiroga, A.R. Sampietro and M.A. Vattuone, J. Ethnopharmacol., 74, 89 (2010); https://doi.org/10.1016/S0378-8741(00)00350-0

S. Dugasani, M.K. Balijepalli, S. Tandra and M.R. Pichika, Pharmacog. Mag., 6, 204 (2010);

https://doi.org/10.4103/0973-1296.66937

G. Sharmila, R.S. Pradeep, K. Sandiya, S. Santhiya, C. Muthukumaran, J. Jeyanthi, N.M. Kumar and M. Thirumarimurugan, J. Mol. Struct., 1165, 288 (2018); https://doi.org/10.1016/j.molstruc.2018.04.011

N. Kannan, K.M. Sakthivel and C. Guruvayoorappan, J. Environ. Pathol. Toxicol. Oncol., 35, 99 (2016); https://doi.org/10.1615/JEnvironPatholToxicolOncol.2016013981

N. Kannan and C. Guruvayoorappan, Int. Immunopharmacol., 16, 57 (2013); https://doi.org/10.1016/j.intimp.2013.03.008

N. Kannan, R.E. Renitta and C. Guruvayoorappan, J. Basic Clin. Physiol. Pharmacol., 21, 157 (2010); https://doi.org/10.1515/jbcpp.2010.21.2.157

J.B. Harborne, Phytochemical Methods, A Guide to Modern Techniques of Plant Analysis, Chapman & Hall Int. Ed.: New York, Ed.: 3 (1998).

C.K. Kokate, Pharmacognosy, Nirali Prakasham: Mumbai, India, Ed.: 16 (2001).

A. Janaki, P.K. Kaleena, D. Elumalai, K. Velu, M. Babu, M. Hemavathi, S. Ravi and C. Arulvasu, J. Pharmacogn. Phytochem., 5, 2403 (2018).

P. Panda, T. Sharma, A. Pal and G. Ghosh, Iran. J. Sci. Technol. Trans. Sci., 43, 1417 (2019); https://doi.org/10.1007/s40995-018-0635-4

S. Rhama and S. Madhavan, J. Drug Deliv. Ther., 2, 83 (2012); https://doi.org/10.22270/jddt.v2i6.284

Issue

Vol. 33 No. 11 (2021): Vol 33 Issue 11, 2021

GC-MS Analysis, Phytochemical Screening and Biological Activity of Bauhinia tomentosa (Linn.)

Corresponding Author(s) : V. Prabhu

Abstract

Keywords

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