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Vol. 33 No. 11 (2021): Vol 33 Issue 11, 2021

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Synthesis of New Class of Functionalized Flavones/Isoxazole Derivatives-Nitrile oxide 1,3-Dipolar Cycloaddition

https://doi.org/10.14233/ajchem.2021.23360
Neeradi Balaiah
Department of Chemistry, Nizam College, Osmania University, Hyderabad-500001, India
Yerrabelly Hemasri
Department of Chemistry, Nizam College, Osmania University, Hyderabad-500001, India

Corresponding Author(s) : Yerrabelly Hemasri

hemay2@yahoo.com

Asian Journal of Chemistry, Vol. 33 No. 11 (2021): Vol 33 Issue 11, 2021

Abstract

A new series of functionalized flavone-isoxazole derivatives have been synthesized from alkyne tethered 3-hydroxy flavone by adopting facile synthetic method, intermolecular nitrile oxide 1,3-dipolar cycloaddition in the presence of eco-friendly sodium hypochloride oxidant under mild reaction conditions. Structures of all the synthesized compounds were established on the basis of 1H NMR, 13C NMR and ESI-mass.

Keywords

Propargyloxy flavone Nitrile oxide Flavone Isoxazole 1,3-Dipolar cycloaddition
Balaiah, N., & Hemasri, Y. (2021). Synthesis of New Class of Functionalized Flavones/Isoxazole Derivatives-Nitrile oxide 1,3-Dipolar Cycloaddition. Asian Journal of Chemistry, 33(11), 2657–2661. https://doi.org/10.14233/ajchem.2021.23360
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