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A New Antiviral Flavone Glycoside from Vernonia cinerea Less.
Corresponding Author(s) : R.N. Yadava
Asian Journal of Chemistry,
Vol. 25 No. 7 (2013): Vol 25 Issue 7
Abstract
A new flavone glycoside (A) m.p. 258-260 ºC, m.f. C33H40O19, [M]+ 740 (FABMS), has been isolated from roots of Vernonia cinerea Less. It was characterized as 5,7,4'-trihydroxy 3'-methoxy flavone-4'-O-a-L-rhamnopyranosyl-(1®4)-O-a-L-arabino-pyranosyl-(1®3)-O-b-D-galactopyranoside by various chemical degradations and spectral analysis which showed antiviral activity alongwith two known compounds luteolin (B) and taxifolin (C).
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- K.R. Kirtikar and B.D. Basu, Indian Med. Plant, 2, 1322 (1945).
- R.P. Rastogi and B.N. Mehrotra, Compendium of Indian Medicinal Plants, vol. 3, p. 669 (1980).
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- R.P. Rastogi and B.N. Mehrotra, Compendium of Indian Medicinal Plants, vol. 1, p. 428 (1990).
- C.D. Douglass, G.L. Morris and S.H. Vendev, J. Am. Chem. Soc., 73, 4023 (1951).
- J. Shinoda, J. Pharm. Soc. Jpn., 48, 214 (1928).
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- E.L. Hirst and J.K.N. Jones, J. Chem. Soc., 129, 1656 (1949).
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References
K.R. Kirtikar and B.D. Basu, Indian Med. Plant, 2, 1322 (1945).
R.P. Rastogi and B.N. Mehrotra, Compendium of Indian Medicinal Plants, vol. 3, p. 669 (1980).
A. Chea, S. Hout, C. Long, L. Marcourt, R. Faure, N. Azas and R. Elias, Chem. Pharm. Bull., 54, 1437 (2006).
T.N. Mishra, R.S. Singh, J. Upadhyay and R. Srivastava, J. Nat. Prod., 47, 368 (1984).
R.P. Rastogi and B.N. Mehrotra, Compendium of Indian Medicinal Plants, vol. 1, p. 428 (1990).
C.D. Douglass, G.L. Morris and S.H. Vendev, J. Am. Chem. Soc., 73, 4023 (1951).
J. Shinoda, J. Pharm. Soc. Jpn., 48, 214 (1928).
L. Yuying and K. Lingyi, Asian J. Trad. Med., 1, 34 (2006).
E.L. Hirst and J.K.N. Jones, J. Chem. Soc., 129, 1656 (1949).
S. Hokomoni, J. Biochem., 66, 205 (1965).
E.L. Hirst and J.K.N. Jones, Chromatogr. Anal., 7, 271 (1949).
N.T.V. Thanh and N.V. Dau, J. Chem., 44, 777 (2006).
Y.L. Li, J. Li, N.L. Wang and X.S. Yao, Molecules, 13, 1931 (2008).