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Vol. 25 No. 6 (2013): Vol 25 Issue 6

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Simultaneous Determination of Five Compounds by HPLC and Its Application to the Suitable Harvest Time for Medicinal Plant Curcuma wenyujin

https://doi.org/10.14233/ajchem.2013.13684
Yuan Zhang
School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang Province, P.R. China
Xiao-Jun Cai
School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang Province, P.R. China
Yu-Ping Xu
School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang Province, P.R. China
Yu Pan
School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang Province, P.R. China
Xiang Zheng
School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, Zhejiang Province, P.R. China

Corresponding Author(s) : Xiang Zheng

xiangzheng1978@yahoo.cn

Asian Journal of Chemistry, Vol. 25 No. 6 (2013): Vol 25 Issue 6

Abstract

The methods for simultaneous determination of five compounds including b-elemene, curcumine, curcumol, curdione and germacrone, were developed using a reversed-phase C18 column. All calibration curves were linear (r > 0.9993) over the range of tested concentration. This method showed good repeatability for the quantification of these five compounds with intra-day and inter-day variations of less than 1.42 and 1.76 %, respectively. Furthermore, the validated method was applied to determine four active components in rhizome extract from different developmental stages of Curcuma wenyujin. The results showed the suitable harvest time can be suggested before and after January, which is helpful to control their quality.

Keywords

Curcuma HPLC Determination
Zhang, Y., Cai, X.-J., Xu, Y.-P., Pan, Y., & Zheng, X. (2013). Simultaneous Determination of Five Compounds by HPLC and Its Application to the Suitable Harvest Time for Medicinal Plant Curcuma wenyujin. Asian Journal of Chemistry, 25(6), 3335–3337. https://doi.org/10.14233/ajchem.2013.13684
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References
  1. J.P. Jiang, Trad. Chin. Med, 2, 62 (2000).
  2. X.H. Nie, Z.H. Ao, G.Y. Yin and W.Y. Tao, Chin. Pharm. Biotechnol., 3, 152 (2003).
  3. F.R. Carvalho, R.C. Vassao, M.A. Nicoletti and D.A. Nicoletti, J. Venom Anim Toxins, 16, 324 (2010).
  4. B.P. Priosoeryanto, E.J. Stephani, R. Sari, L.K. Darusman, E.D. Purwakusumah, W. Nurcholis and R. Tiuria, Thai. J. Vet. Med., 39, 447 (2009).
  5. H.J. Kim, H.S. Yoo, J.C. Kim, C.S. Park, M.S. Choi, M. Kim, H. Choi, J.S. Min, Y.S. Kim, S.W. Yoon and J.K. Ahn, J. Ethnopharmacol., 124, 189 (2009).
  6. Q. Ming, F. Sun, J.W. Liu, Z.Q. Liu, S.Q. Zhang, Y.Q. Le and S.Y. Xing, Chin. J. Gerontol., 24, 267 (2004).
  7. Q. Xia, Z.G. Huang, S.P. Li, P. Zhang, J. Wang, L.N. He, Chin. Pharmacol. Bull., 20, 357 (2004).
  8. A. Ramirez Bosca, A. Soler, M.A.C. Gutierrez, J.L. Alvarez and E.Q. Almagro, Age, 18, 167 (1995).
  9. X. Chen, H.Y. Zhong, H. Zhu, J.H. Zeng and P. Dai,Int. J. Biol. Macromol., 44, 138 (2009).
  10. A.K. Singh, G.S. Sidhu, T. Deepa and R.K. Maheshwari, Cancer. Lett., 107, 109 (1996).
  11. E.H. South, J.H. Exon and K. Hendrix, Immunopharm. Immunot., 19, 105 (1997).
  12. K. Spelman, J. Burns, D. Nichols, N. Winters, S. Ottersberg and M. Tenborg, Altern. Med. Rev., 11, 128 (2006)
  13. K. Sompamit, U. Kukongviriyapan, S. Nakmareong, P. Pannangpetch and V. Kukongviriyapan, Eur. J. Pharmacol., 616, 192 (2009).
  14. L.P. Yarru, R.S. Settivari, N.K.S. Gowda, E. Antoniou, D.R. Ledoux and G.E. Rottinghaus, Poultry Sci., 88, 2620 (2009).
  15. Y. Wang and M.Z. Wang, Acta Pharmacol. Sin., 36, 849 (2001).
  16. M.T. Huang, W. Ma, P. Yen, J.G. Xie, J.K. Han, K. Frenkel, D. Grunberger and A.H. Conney, Carcinogenesis, 18, 83 (1997).
  17. H. Matsuda, K. Ninomiya, T. Morikawa and M. Yoshikawa, Bioorg. Med. Chem. Lett., 8, 339 (1998).
  18. H.S. Samaha, G.J. Kelloff, V. Steele, C.V. Rao and B.S. Reddy, Cancer Res., 57, 1301 (1997).
  19. S. Zheng, H. Yang, S.Z. Zhang, X.P. Wang, L.L. Yu, J.Q. Lu and J. Li, J. Cell. Biochem., 67, 106 (1997).
  20. P.S. Xie and A.Y. Leung, J. Chromatogr. A, 1216, 1933 (2009).
  21. K.M. Gong, J. Ren, S.H. Tang, B.L. Tang, H.Q. Zhao and M.Y. Jin, Chin.Tradit. Herb. Drugs, 36, 1331 (2005).
  22. J.Z. Wang, Y.F. Lou, J.F. Lu, X.P. He, L.X. Zheng and X.L. Deng, Chin. J. Clin. Pharm., 10, 107 (2001).
  23. Y. Xie, T.J. Hang, Z.X. Zhang and D.K. An, Chin. Tradit. Herb. Drugs, 3, 600 (2001).
  24. C.H. Deng, J. Ji, N. Li, Y.J. Yu, G.L. Duan and X.M. Zhang, J. Chromatogr. A, 1117, 115 (2006).
  25. F.Q. Yang, S.P. Li, Y. Chen, Q.Q. Liu, W.Y. Tao, D.T. Xia and Z.H. Qiang, Chin. J. Pharm. Anal., 25, 827 (2005).
  26. F.Q. Yang, S.P. Li, J. Zhao, S.C. Lao and Y.T. Wang, J. Pharm. Biomed. Anal., 43, 73 (2007).
  27. B. Avula, Y.H. Wang, T.J. Smillie and I.A. Khan, Planta Medica, 75, 437 (2009).
  28. R. Bos, T. Windono, H.J. Woerdenbag, Y.L. Boersma, A. Koulman and O. Kayser, Phytochem. Anal., 18, 118 (2007).
  29. F.Q. Yang, Y.T. Wang and S.P. Li, J. Chromatogr. A, 1134, 226 (2006).
  30. N. Baldovini, F. Tomi and J. Casanova, Phytochem. Anal., 12, 58 (2001).
  31. Y.Z. Liang, P. Xie and K. Chan, J. Chromatogr. B, 812, 53 (2004).
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