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Synthesis, Characterization and Antimicrobial Activity of First Row Transition Metal(II) Complexes of Novel Schiff Base Derived from Sulfapyridine and Pyridine-2-Aldehyde
Corresponding Author(s) : I. Rama
Asian Journal of Chemistry,
Vol. 25 No. 6 (2013): Vol 25 Issue 6
Abstract
A new Schiff base ligand (N-pyridin-2-yl-4-[(pyridin-2-yl)methyl amino]benzene sulfonamide) (L) was prepared by the reaction between sulfapyridine and pyridine-2-aldehyde. The ligand is bidentate by coordinating through pyridinyl nitrogen and azomethine nitrogen atom with Co(II), Ni(II), Cu(II), Zn(II) and Mn(II) chlorides. The complexes were synthesized and characterized by elemental analysis, molar conductance, magnetic moment, IR, H1 NMR and electronic spectral data. These complexes were screened in vitro antibacterial activity against the test microorganisms Staphylococcus aureus, Pseudomonas aeruginosa and fungi Candida albicans and Aspergillus niger. The results of these studies revealed that all complexes exhibit significant to moderate antimicrobial activity.
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- P.J. Sadler, Adv. Inorg. Chem., 36, 1 (1991).
- M.J. Abrams and B.A. Murrer, Science, 261, 725 (1993).
- G.D. Tiwari and M.N. Mishra, Curr. Sci. 49, 8 (1980).
- K. Lal and R.K. Shukla, J. Indian Chem. Soc., 58, 115 (1981).
- A.K. Varshney and J.P. Tandon, Polyhedron, 5, 1853 (1986).
- K.S. Siddique, R.I. Kureshy, S. Tabassum and S. Zaidi, Inorg. Chem. Acta, 151, 95; Chem. Abstr., 108 (1988).
- N. Raman, S.J. Raja, J. Joseph, A. Sakthivel and J.D. Raja, J. Chil. Chem. Soc., 53, 1599 (2008).
- K. Singh, M.S. Barwa and P. Tyagi, Eur. J. Med. Chem., 41, 147 (2006).
- W. Wang, H. Li, J. Wang and L.S. Zu, J. Am. Chem. Soc., 128, 10354 (2006).
- H.L. Singh, M. Sharma and A.K. Varshney, ACGC Chem. Res. Commun., 8, 35 (1998); Chem. Abstr., 131, 110367 (1999).
- Indian Pharmacopoeia, IIA, 105 (1996).
- W.I. Geary, Coord. Chem. Rev., 7, 81 (1971).
- F.A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry, John Wiley & Sons, New York, edn. 5, p. 631 (1988).
- B.C. Khade, W.N. Jadhav, R.P. Pawar, A.U. Deshmukh, S.R. Kundikar, V.J. Kulkarni and M.V. Lokhande, Asian J. Chem., 16, 947 (2004).
- R.C. Maurya, D.D. Mishra and S. Mukherjee, Synth. React. Inorg. Met. Org. Chem., 21, 1107 (1991).
- S. Chandra, M. Tyagi and K. Sharma, J. Iran. Chem. Soc., 6, 310 (2009).
- I.J. Bellamy, The Infra Red Spectra of Complex Molecules, New York; John Wiley (1971).
- J.R. Ferrero, Low-Frequency Vibrations of Inorganic and Coordination Compounds, Wiley, New York (1971).
- G.R. Burns, Inorg. Chem., 7, 277 (1968).
- R.C. Maurya and P. Patel, Spectr. Lett., 32, 213 (1999).
- D.J. Pasto, Organic Structure Determination, London, UK, Prentice Hall (1969).
- Z.H. Chohan and M.M. Naseer, App. Organomet. Chem., 21, 728 (2007).
- J.D. Lee, Concise Inorganic chemistry, Blackwell Science, Reprint, edn. 5, p. 967 (1999).
- R.S. Srivastava, Inorg. Chim. Acta, 56, 65 (1944).
References
P.J. Sadler, Adv. Inorg. Chem., 36, 1 (1991).
M.J. Abrams and B.A. Murrer, Science, 261, 725 (1993).
G.D. Tiwari and M.N. Mishra, Curr. Sci. 49, 8 (1980).
K. Lal and R.K. Shukla, J. Indian Chem. Soc., 58, 115 (1981).
A.K. Varshney and J.P. Tandon, Polyhedron, 5, 1853 (1986).
K.S. Siddique, R.I. Kureshy, S. Tabassum and S. Zaidi, Inorg. Chem. Acta, 151, 95; Chem. Abstr., 108 (1988).
N. Raman, S.J. Raja, J. Joseph, A. Sakthivel and J.D. Raja, J. Chil. Chem. Soc., 53, 1599 (2008).
K. Singh, M.S. Barwa and P. Tyagi, Eur. J. Med. Chem., 41, 147 (2006).
W. Wang, H. Li, J. Wang and L.S. Zu, J. Am. Chem. Soc., 128, 10354 (2006).
H.L. Singh, M. Sharma and A.K. Varshney, ACGC Chem. Res. Commun., 8, 35 (1998); Chem. Abstr., 131, 110367 (1999).
Indian Pharmacopoeia, IIA, 105 (1996).
W.I. Geary, Coord. Chem. Rev., 7, 81 (1971).
F.A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry, John Wiley & Sons, New York, edn. 5, p. 631 (1988).
B.C. Khade, W.N. Jadhav, R.P. Pawar, A.U. Deshmukh, S.R. Kundikar, V.J. Kulkarni and M.V. Lokhande, Asian J. Chem., 16, 947 (2004).
R.C. Maurya, D.D. Mishra and S. Mukherjee, Synth. React. Inorg. Met. Org. Chem., 21, 1107 (1991).
S. Chandra, M. Tyagi and K. Sharma, J. Iran. Chem. Soc., 6, 310 (2009).
I.J. Bellamy, The Infra Red Spectra of Complex Molecules, New York; John Wiley (1971).
J.R. Ferrero, Low-Frequency Vibrations of Inorganic and Coordination Compounds, Wiley, New York (1971).
G.R. Burns, Inorg. Chem., 7, 277 (1968).
R.C. Maurya and P. Patel, Spectr. Lett., 32, 213 (1999).
D.J. Pasto, Organic Structure Determination, London, UK, Prentice Hall (1969).
Z.H. Chohan and M.M. Naseer, App. Organomet. Chem., 21, 728 (2007).
J.D. Lee, Concise Inorganic chemistry, Blackwell Science, Reprint, edn. 5, p. 967 (1999).
R.S. Srivastava, Inorg. Chim. Acta, 56, 65 (1944).