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Vol. 25 No. 6 (2013): Vol 25 Issue 6

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Isolation of Vomifoliol: A Megastigmane from Leaves of Antidesma ghaesembilla

https://doi.org/10.14233/ajchem.2013.13872
S. Maria
Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
F. Islam
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
N. Qais
Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
C.M. Hasan
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh

Corresponding Author(s) : F. Islam

farhana_p40@yahoo.com

Asian Journal of Chemistry, Vol. 25 No. 6 (2013): Vol 25 Issue 6

Abstract

The leaves of Antidesma ghaesembilla Gaertn (Phyllanthaceae) was subjected to phytochemical investigation. The powdered leaves were extracted with ethanol and then partitioned among petroleum ether, carbon tetrachloride and chloroform. Fractionation of the chloroform extracts affords the isolation and structural elucidation of vomifoliol. The separation of the chemical component was carried out by different chromatographic techniques and the structure was elucidated by nuclear magnetic resonance (1H NMR) as well as by mass spectrometry.

Keywords

Antidesma ghaesembilla Phyllanthaceae Vomifoliol 1H NMR
Maria, S., Islam, F., Qais, N., & Hasan, C. (2013). Isolation of Vomifoliol: A Megastigmane from Leaves of Antidesma ghaesembilla. Asian Journal of Chemistry, 25(6), 3533–3534. https://doi.org/10.14233/ajchem.2013.13872
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References
  1. F. Pax and P. Hoffmann, In ed.:A. Engler, Euphorbiaceae-PhyllanthoideaePhyllanthae, in Das Pflanzenreich 81, Wilhelm Engelmann, Leipzig, Vol. 1 (1922).
  2. J.F. Caius, The Medicinal and Poisonous Plants of India, Scientific Publishers, Jodhpur, India, p. 528 (1986).
  3. B.C. Vanwagenen, R. Larsen, J.H. Cardellina II, D. Randazzo, Z.C. Lidert and C. Swithenbank, J. Org. Chem., 58, 335 (1993).
  4. J.C. Coll and B.F. Bowden, J. Nat. Prod., 49, 934 (1986).
  5. R.G. Reid and S.D. Sarker, Nat. Prod. Isolation, 4, 111 (1998).
  6. Q.T. Liu and J.L. Kinderlerer, J. Chromatogr., 855, 617 (1999).
  7. K.L. Stuart and R.B.W. Ming, Phytochem. Reports, 14, 594 (1975).
  8. S. Hammami, H.B. Jannet, A. Bergaoui, L. Ciavatta, G. Cimino and Z. Mighri, Molecules, 9, 602 (2004).
  9. S. Oksuz, A. Ulubellen and A. Barla, Turk. J. Chem., 26, 457 (2002).
  10. K.L. Stuart and L.B. Coke, Planta, 122, 307 (1975).
  11. J.M. Zhou, G.Y. Geng, G. Batist and J.H. Wu, Bioorg. Med. Chem. Lett., 19, 1183 (2009).
  12. J.R. Liu, B.F. Yang, B.Q. Chen, Y.M. Yang, H.W. Dong and Y.Q. Song, World J. Gastroenterol., 10, 167 (2004).
  13. W.L. Chen, Q.F. Liu, J. Wang, J.P. Zuo, Z.X. Zhu and W.M. Zhao, Planta Med., 72, 143 (2006).
  14. J.R. Liu, B.F. Yang, B.Q. Chen, H.W. Dong, Y.Q. Song, C.H. Sun, Q. Wang and G. Song, World J. Gastroenterol., 10, 348 (2004).
  15. J.R. Liu, X.R. Sun, H.W. Dong, C.H. Sun, W. G. Sun, B.Q. Chen, Y.Q. Song and B.F. Yang, Int. J. Cancer, 122, 268 (2008).
  16. S.G. Yu, P.J. Anderson and C.E. Elson, J. Agric. Food Chem., 43, 2144 (1995).
  17. H. Ito, E. Kobayashi, S.H. Li, T. Hatano, D. Sugita, N. Kubo, S. Shimura, Y. Ito, H. Tokuda and H. Nishino, J. Agric. Food Chem., 50, 2400 (2002).
  18. I. Kubo and Y. Morimitsu, J. Agric. Food Chem., 43, 1626 (1995).
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