Copyright (c) 2013 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Synthesis and Spectral Studies of Some 2-Oxopyrimidine-1(2H)-yl]-pyrrolidine-2,5-dione Derivatives
Corresponding Author(s) : Zülbiye Önal
Asian Journal of Chemistry,
Vol. 25 No. 5 (2013): Vol 25 Issue 5
Abstract
1-Amino-5-(4-methylbenzoyl)-4-(4-methylphenyl)pyrimidine-2(1H)-one/-thione (1a,b) reacted with various carboxylic anhydrides (2a-d) under different conditions and given the new amide and imide derivatives (3a-h). The newly synthesized compounds were characterized by elemental analysis, IR, 1H and 13C NMR spectral data. All the compounds were compared with their previous analogues.
Keywords
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
- R.S. Varma, Green Chem., 1, 43 (1999).
- C.O. Kappe, Tetrahedron, 46, 6937 (1993).
- W. Xie, Y. Jin and P.G. Wang, Chemtech., 2, 23 (1999).
- C.O. Kappe, W.M.F. Fabian and M.A. Semones, Tetrahedron, 53, 2803 (1997).
- G.J. Grover, S. Dzwonczyk, D.M. Mc Mullen, C.S. Normadinam, P.G. Sleph and S.J. Moreland, Cardiovasc. Pharmacol., 26, 289 (1995).
- C.D. Selassie, R. Poe, M. Li and C. Hansch, J. Med. Chem., 34, 46 (1991).
- E.L. Burdge, Pest Manag. Sci., 56, 245 (2000).
- K. Parfitt, Martindale, Pharmaceutical Press, London, edn 32 (1999).
- I. Yildirim and I. Koca, Kuwait J. Sci. Eng., 32, 49 (2005).
- Z. Önal and I. Yildirim, Heterocycl. Commun., 13, 113 (2007).
- Z. Önal, E. Saripinar and I.Ö. Ilhan, J. Heterocycl. Chem., 38, 397 (2001).
- Z. Önal and B. Altural, Turk. J. Chem., 23, 401 (1999).
- Z. Önal and A.C. Daylan, Asian J. Chem., 19, 1455 (2007).
- Z. Onal, N. Atli and I.O. Ilhan, Heterocycl. Commun., 15, 385 (2009).
- Z. Onal, H. Ceran and E. Sahin, Heterocycl. Commun., 14, 245 (2008).
- Z. Onal, I. Yildirim, F. Kandemirli and T. Arslan, Struct. Chem., 21, 809 (2010).
- Z. Onal, H. Ceran and E. Sahin, Heterocycl. Commun., 14, 245 (2008).
References
R.S. Varma, Green Chem., 1, 43 (1999).
C.O. Kappe, Tetrahedron, 46, 6937 (1993).
W. Xie, Y. Jin and P.G. Wang, Chemtech., 2, 23 (1999).
C.O. Kappe, W.M.F. Fabian and M.A. Semones, Tetrahedron, 53, 2803 (1997).
G.J. Grover, S. Dzwonczyk, D.M. Mc Mullen, C.S. Normadinam, P.G. Sleph and S.J. Moreland, Cardiovasc. Pharmacol., 26, 289 (1995).
C.D. Selassie, R. Poe, M. Li and C. Hansch, J. Med. Chem., 34, 46 (1991).
E.L. Burdge, Pest Manag. Sci., 56, 245 (2000).
K. Parfitt, Martindale, Pharmaceutical Press, London, edn 32 (1999).
I. Yildirim and I. Koca, Kuwait J. Sci. Eng., 32, 49 (2005).
Z. Önal and I. Yildirim, Heterocycl. Commun., 13, 113 (2007).
Z. Önal, E. Saripinar and I.Ö. Ilhan, J. Heterocycl. Chem., 38, 397 (2001).
Z. Önal and B. Altural, Turk. J. Chem., 23, 401 (1999).
Z. Önal and A.C. Daylan, Asian J. Chem., 19, 1455 (2007).
Z. Onal, N. Atli and I.O. Ilhan, Heterocycl. Commun., 15, 385 (2009).
Z. Onal, H. Ceran and E. Sahin, Heterocycl. Commun., 14, 245 (2008).
Z. Onal, I. Yildirim, F. Kandemirli and T. Arslan, Struct. Chem., 21, 809 (2010).
Z. Onal, H. Ceran and E. Sahin, Heterocycl. Commun., 14, 245 (2008).