Issue

Vol. 25 No. 5 (2013): Vol 25 Issue 5

Copyright (c) 2013 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Thermal and Interfacial Studies of Binary Alloys of Nicotinamide-b-Naphthol Drug System

https://doi.org/10.14233/ajchem.2013.13344
H. Shekhar
Department of Chemistry, Veer Kunwar Singh University, Ara-802 301, India
Vishnu Kant
Department of Chemistry, Veer Kunwar Singh University, Ara-802 301, India

Corresponding Author(s) : Vishnu Kant

imvishnukant@gmail.com

Asian Journal of Chemistry, Vol. 25 No. 5 (2013): Vol 25 Issue 5

Abstract

The study reports the thermal and growth investigation of binary alloys represented by nicotinamide with b-naphthol. The solid-liquid equilibrium data determined by Thaw-melt method with their corresponding compositions construct the solid-liquid phase diagram which suggests simple eutectic behaviour is followed by the binary system. The activity coefficient model based on enthalpy of fusion was employed to calculate the excess thermodynamic properties that of gE, hE and sE, which predict the nature of molecular interaction, ordering and stability between the components. The partial and integral mixing functions DGM, DHM, DSM of the eutectic and noneutectic alloys were also computed. The driving force of nucleation during solidification (DGv), critical size or radius (r*) and the critical free energy of nucleation (DG*) at different undercoolings have been determined. Using heat of fusion data the solid-liquid interface energy (s), grain boundary energy (sgb), the Gibbs-Thomson coefficient (t) and roughness parameter (a) of all the alloys are evaluated by numerical method. Interface morphology of the alloys follows the Jackson's surface roughness (a) theory and predicts the faceted growth proceeds in all the alloys.

Keywords

Phase diagram Thermodynamic excess and mixing functions Critical radius Interfacial energy Roughness parameter
Shekhar, H., & Kant, V. (2012). Thermal and Interfacial Studies of Binary Alloys of Nicotinamide-b-Naphthol Drug System. Asian Journal of Chemistry, 25(5), 2441–2446. https://doi.org/10.14233/ajchem.2013.13344
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. M. Knip, I.F. Douek and W.P. Moore, Diabetologia, 43, 1337 (2000).
  2. T. Hakozaki, L. Minwalla and J. Zhung, Br. J. Dermatol., 147, 20 (2002).
  3. S. Akbulut, Y. Ocak, K. Keslioglu and N. Marasli, Appl. Surf. Sci., 255, 3594 (2009).
  4. R. Kumar, V. Ulagendran, V. Kannappan and S. Jayakumar, Fluid Phase Equilibiria, 307, 113 (2011).
  5. Y. Dwivedy, S. Kant, U.S. Rai and R.N. Rai, J. Fluorescence, 21, 1255 (2011).
  6. B.L. Sharama, S. Tandon and S. Gupta, Cryst. Res. Technol., 44, 258 (2009).
  7. R.P. Rastogi and K.T. Rama Verma, J. Chem. Soc., 2097 (1956).
  8. H. Shekhar, K.B. Pandey and V. Kant, J. Natl. Acad. Sci. Lett., 33, 153 (2010).
  9. A. Krajewska-Cizio, Thermochim. Acta, 158, 317 (1990).
  10. U.S. Rai and H. Shekhar, Asian J. Chem., 11, 453 (1999).
  11. J. Sangester, J. Phys. Chem. Ref. Data, 23, 295 (1994).
  12. R. Nieto, M.C. Gonozalez and F. Herrero, Am. J. Phys., 67, 1096 (1999).
  13. H. Shekhar and S.S. Salim, J. Nat. Acad. Sci. Lett., 34, 117 (2011).
  14. J. Wisniak and A. Tamir, Mixing and Excess Thermodynamic Properties (A Literature Source Book), Phys. Sci. Data 1, Elsevier, New York (1978).
  15. T. Agarwal, P. Gupta, S.S. Das, A. Gupta and N.B. Singh, J. Chem. Eng. Data, 55, 4206 (2010).
  16. M. Shamsuddin, S.B. Singh and A. Nasar, Thermochim. Acta, 316, 11 (1998).
  17. N.B. Singh and M.E. Glicksman, J. Cryst. Growth, 98, 573 (1989).
  18. D. Turnbull, J. Chem. Phys., 18, 768 (1950).
  19. J.D. Hunt and S.Z. Lu, in ed.: Ed. D.T.J. Hurle, Hand Book of Crystal Growth, Elsevier, Amsterdam (1994).
  20. G.A. Chadwick, Metallography of Phase Transformation, Butterworths, London, p. 61 (1972).
  21. W.R. Wilcox, J. Crystal Growth, 26, 153 (1974).
  22. M. Gunduz and J.D. Hunt, Acta Metall., 37, 1839 (1989).
  23. Y. Ocak, S. Akbulut, K. Keslioglu and N. Marasli, J. Colloid Interf. Sci., 320, 555 (2008).
  24. J.D. Hunt and K.A. Jackson, Trans. Metall. Soc. AIME, 236, 843 (1966).
  25. H. Shekhar and V. Kant, J. Indian Chem. Soc., 88, 947 (2011).
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 0