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Vol. 25 No. 4 (2013): Vol 25 Issue 4

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Synthesis, Characterization and Biological Activity of Copper Complex

https://doi.org/10.14233/ajchem.2013.13294
Jin Huang
Life and Environment Science College, Shanghai Normal University, Shanghai 200234, P.R. China ; School of chemistry and chemical engineering, Huaiyin Normal University, Huai'an 318020, P.R. China
Zhihui Shen
Life and Environment Science College, Shanghai Normal University, Shanghai 200234, P.R. China
Xiaoke Chen
Life and Environment Science College, Shanghai Normal University, Shanghai 200234, P.R. China
Yinghao Xu
Life and Environment Science College, Shanghai Normal University, Shanghai 200234, P.R. China
Dongfang Xu
Life and Environment Science College, Shanghai Normal University, Shanghai 200234, P.R. China
Qizhuang He
Life and Environment Science College, Shanghai Normal University, Shanghai 200234, P.R. China

Corresponding Author(s) : Dongfang Xu

xdf26@shnu.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 4 (2013): Vol 25 Issue 4

Abstract

A novel dinuclear copper complex was synthesized and characterized by elemental analysis, molar conductance, FT-IR, UV-VIS, TG-DTA and TEM. The antibacterial activity test indicated that the complex exhibited antibacterial ability against Escherichia coli and Staphylococcus aureus with broad antimicrobial spectrums. (MIC was ca. 150 and 120 μg mL-1, respectively). The antitumor activity of the copper complex indicated that the complex exhibited potent antitumor effects against K562 cell lines by MTT method. The IC50 value of the complex was ca. 0.01 μg mL-1.

Keywords

Dinuclear copper complex Antibacterial Antitumor
Huang, J., Shen, Z., Chen, X., Xu, Y., Xu, D., & He, Q. (2012). Synthesis, Characterization and Biological Activity of Copper Complex. Asian Journal of Chemistry, 25(4), 2043–2046. https://doi.org/10.14233/ajchem.2013.13294
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