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Vol. 25 No. 4 (2013): Vol 25 Issue 4

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Isolation and Biological Activities of Furanoflavones from the Roots of Codonopsis cordifolioidea

https://doi.org/10.14233/ajchem.2013.13291
Hongqiong Leng
School of Pharmaceutical Science & Yunan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Guangyu Yang
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Yongkuan Chen
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, P.R. China
Yadong Guo
School of Pharmaceutical Science & Yunan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, P.R. China
Zhangyu Chen
School of Pharmaceutical Science & Yunan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, P.R. China ; China Tobacco Yunnan Industry Company (Ltd.), Kunming 650000, P.R. China

Corresponding Author(s) : Yadong Guo

yadong_guo@yahoo.com.cn; ygy1110@163.com

Asian Journal of Chemistry, Vol. 25 No. 4 (2013): Vol 25 Issue 4

Abstract

A new furanoflavone, cordifoliketone C (1), together with three known furanoflavones (2-4), were isolated from the roots of Codonopsis cordifolioidea. Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. Compounds 1-4 were tested for their anti-HIV-1 activity and antitobacco mosaic virus activity, respectively. The results showed that compounds 1-4 have modest anti-HIV-1 activity and anti-tobacco mosaic virus activity, respectively.

Keywords

Codonopsis cordifolioidea Furanoflavones Anti-HIV-1 activity Antitobacco mosaic virus activity
Leng, H., Yang, G., Chen, Y., Guo, Y., & Chen, Z. (2012). Isolation and Biological Activities of Furanoflavones from the Roots of Codonopsis cordifolioidea. Asian Journal of Chemistry, 25(4), 2024–2026. https://doi.org/10.14233/ajchem.2013.13291
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