Issue

Vol. 25 No. 3 (2013): Vol 25 Issue 3

Copyright (c) 2013 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Studies on the Metabolites of a Fungal Endophyte Penicillium sp. HS-5 from Huperzia serrata

https://doi.org/10.14233/ajchem.2013.12350
You-Min Ying
College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P.R. China
Wei-Guang Shan
College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P.R. China
Wen-Hong Liu
Zhejiang Chinese Medical University, Hangzhou 310053, P.R. China
Zha-Jun Zhan
College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P.R. China

Corresponding Author(s) : Zha-Jun Zhan

zjnpr@zjut.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 3 (2013): Vol 25 Issue 3

Abstract

Nine compounds 1-9 were isolated from the broth of the strain Penicillium sp. HS-5, a fungal endophyte living in Huperzia serrata. Structures of the isolated compounds were identified as Sumiki's acid (1), acetyl Sumiki's acid (2), 2-furoic acid (3), kojic acid (4), 4-hydroxybenzonic acid (5), adenosine (6), adenine (7), thymine (8) and ergosterol (9) by NMR and MS analysis as well as by comparison of their physio-chemical and spectroscopic data with literatures. Compounds 1-4 were isolated for the first time from a fungal endophyte of Huperzia serrata and subjected to an antibacterial assay against S. aureus ATCC 29213, a MRSA strain.

Keywords

Endophyte Huperzia serrata Antibacterial Sumiki's acid
Ying, Y.-M., Shan, W.-G., Liu, W.-H., & Zhan, Z.-J. (2012). Studies on the Metabolites of a Fungal Endophyte Penicillium sp. HS-5 from Huperzia serrata. Asian Journal of Chemistry, 25(3), 1208–1210. https://doi.org/10.14233/ajchem.2013.12350
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. R.X. Tan and W.X. Zou, Nat. Prod. Rep., 18, 448(2001).
  2. B. Schulz, C. Boyle, S. Draeger, A.K. Römmert and K. Krohn, Mycol. Res., 106, 996 (2002).
  3. G. Strobel, B. Daisy, U. Castillo and J. Harper, J. Nat. Prod., 67, 257 (2004).
  4. W.G. Shan, Y.M. Ying, H.N. Yu, W.H. Liu and Z.J. Zhan, Helv. Chim. Acta, 93, 722 (2010).
  5. R. Jadulco, P. Proksch, V. Wray, Sudarsono, A. Berg and U. Gräfe, J. Nat. Prod., 64, 527 (2001).
  6. V. Nair, V. Varghese, R.R. Paul, A. Jose, C.R. Sinu and R.S. Menon, Org. Lett., 12, 2653 (2010).
  7. X.F. Li, J.H. Jeong, K.T. Lee, J.R. Rho, H.D Choi, J.S. Kang and B.W. Son, Arch. Pharm. Res., 26, 532 (2003).
  8. F. Wang and J.K. Liu, Nat. Prod. Res. Dev., 16, 204 (2004).
  9. S.M. Zhou, K. Zhou and D.J. Xiao, Chin. J. Mar. Drugs, 24, 31 (2005).
  10. Q. Chen, L.J. Wu and L.J. Ruan, J. Shenyang Pharm. Univ., 19, 257 (2002).
  11. G.C. Su, S. Zhang and S.H. Qi, Chin. Tradit. Herbal Drugs, 39, 1606 (2008).
  12. C. Moreau, R. Durand, S. Razigade, J. Duhamet, P. Faugeras, P. Rivalier, P. Ros and G. Avignon, Appl. Catal. A, 145, 211 (1996).
  13. X. Qian, M.R. Nimlos, M. Davis, D.K. Johnson and M.E. Himmel, Carbohydr. Res., 340, 2319 (2005).
  14. J.N. Chheda, Y. Román-Leshkov and J.A. Dumesic, Green Chem., 9, 342 (2007).
  15. T. Yabuta, J. Chem. Soc., 125, 575 (1924).
  16. R. Bentley, Nat. Prod. Rep., 23, 1046 (2006).
  17. A.W. West, W.D. Grant and G.P. Sparling, Soil Biol. Biochem., 19, 607 (1987).
  18. S.Y. Newell, T.L. Arsuffi and R.D. Fallon, Appl. Environ. Microbiol., 54, 1876 (1988).
  19. L.M. Seitz, H.E. Mohr, R. Burroughs and D.B. Sauer, Cereal Chem., 54, 1207 (1977).
  20. F. Martin, C. Delaruelle and J.-L. Hilbert, Mycol. Res., 94, 1059 (1990).
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 0