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Synthesis of Azabicyclo[3.1.0]amine Analogues of Anacardic Acid as Potent Antibacterial Agents
Corresponding Author(s) : Srinivasa Rao Alapati
Asian Journal of Chemistry,
Vol. 25 No. 2 (2013): Vol 25 Issue 2
Abstract
Azabicyclo[3.1.0]amine analogues of anacardic acid (16a, 16b, 18a, 18b, 19 and 19b) were synthesized from anacardic acid and tested for their antibacterial activity against Gram positive and Gram negative bacteria. Most of the compounds are having potency at par with ampicillin and inferior with other standard drugs.
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- R. Paramshivappa, P.P. Kumar, P.J. Vijayathil and A.S. Rao, J. Agric. Food Chem., 49, 2548 (2001).
- P.P. Kumar, R. Paramshivappa, P.J. Vijayathil, P.V.S. Rao and A.S. Rao, J. Agric. Food Chem., 50, 4705 (2002).
- I. Kubo, H. Muroi and M. Himejima, J. Agric. Food Chem., 41, 1016 (1993).
- I. Kubo, K. Nihei and K. Tsuzimoto, J. Agric. Food Chem., 51, 7624 (2003).
- J. Rejman and A. Kozubek, J. Agric. Food Chem., 52, 246 (2004).
- I. Kubo and T.J. Ha, J. Agric. Food Chem., 53, 4350 (2005).
- R. Paramshivappa, P.P. Kumar, P.V.S. Rao and A.S. Rao, J. Agric. Food Chem., 50, 7709 (2002).
- (a) P.P. Kumar, R. Paramshivappa, P.V.S. Rao and A.S. Rao, PCT WO 105854 A2 (2003). (b) P.P. Kumar, R.Paramshivappa, P.V.S. Rao and A.S. Rao, PCT WO 062201 A1 (2003).
- B.N. Swamy, T.K. Suma, C.V. Rao and G.C. Reddy, Eur. J. Med. Chem., 42, 420 (2007).
- D.J. Schultz, C. Olsen, G.A. Cobbs, N.J. Stolowich and M.M. Parrott, J. Agric. Food Chem., 54, 7522 (2006).
- B. Sung, K.P. Manoj, K.S. Ahn, T. Yi, M.M. Chaturvedi, M. Liu and B.B. Agarawal, Blood, 111, 4880 (2008).
- I. Kubo, M. Ochi, P.C. Viera and S. Komastu, J. Agric. Food Chem., 41, 1012 (1993).
- P. Begum, Y. Hashidoko, Md. T. Islam, Y. Ogawa and S. Tahara, Z. Naturforsch, 57c, 874 (2002).
- A. Harikishore, B.M. Vedamurthy, K. Mantelingu, S. Agarwal, B.A. A. Reddy, S. Roy, K.S. Rangappa and T.K. Kundu, J. Med. Chem., 51, 792 (2008).
- V. Chandregowda, A. Kush and G.C. Reddy, Eur. J. Med. Chem., 44, 2711 (2009).
- R.K. Vempati, N.S. Reddy, S.R. Alapati and P.K. Dubey, Der Pharma Chem., 3, 500 (2011).
- (a) T. Norris, T.F. Braish, M. Butters, K.M. Devries, J.M. Hawkins, S.S. Masset and P.R. Rose, D. Santafianos and C. Sklavounos, J. Chem. Soc., Perkin Trans. I, 1615 (2000); (b) Q. Sun, R. Zhu, F.W. Foss Jr. and T.L. Macdonald, Bioorg. Med. Chem. Lett., 17, 6682 (2007); (c) G. Madhusudan, V. Balaraju, T. Rajesh, B.V. Narayana and R.N. Reddy, Indian J. Chem., 48B, 569-573 (2009).
References
R. Paramshivappa, P.P. Kumar, P.J. Vijayathil and A.S. Rao, J. Agric. Food Chem., 49, 2548 (2001).
P.P. Kumar, R. Paramshivappa, P.J. Vijayathil, P.V.S. Rao and A.S. Rao, J. Agric. Food Chem., 50, 4705 (2002).
I. Kubo, H. Muroi and M. Himejima, J. Agric. Food Chem., 41, 1016 (1993).
I. Kubo, K. Nihei and K. Tsuzimoto, J. Agric. Food Chem., 51, 7624 (2003).
J. Rejman and A. Kozubek, J. Agric. Food Chem., 52, 246 (2004).
I. Kubo and T.J. Ha, J. Agric. Food Chem., 53, 4350 (2005).
R. Paramshivappa, P.P. Kumar, P.V.S. Rao and A.S. Rao, J. Agric. Food Chem., 50, 7709 (2002).
(a) P.P. Kumar, R. Paramshivappa, P.V.S. Rao and A.S. Rao, PCT WO 105854 A2 (2003). (b) P.P. Kumar, R.Paramshivappa, P.V.S. Rao and A.S. Rao, PCT WO 062201 A1 (2003).
B.N. Swamy, T.K. Suma, C.V. Rao and G.C. Reddy, Eur. J. Med. Chem., 42, 420 (2007).
D.J. Schultz, C. Olsen, G.A. Cobbs, N.J. Stolowich and M.M. Parrott, J. Agric. Food Chem., 54, 7522 (2006).
B. Sung, K.P. Manoj, K.S. Ahn, T. Yi, M.M. Chaturvedi, M. Liu and B.B. Agarawal, Blood, 111, 4880 (2008).
I. Kubo, M. Ochi, P.C. Viera and S. Komastu, J. Agric. Food Chem., 41, 1012 (1993).
P. Begum, Y. Hashidoko, Md. T. Islam, Y. Ogawa and S. Tahara, Z. Naturforsch, 57c, 874 (2002).
A. Harikishore, B.M. Vedamurthy, K. Mantelingu, S. Agarwal, B.A. A. Reddy, S. Roy, K.S. Rangappa and T.K. Kundu, J. Med. Chem., 51, 792 (2008).
V. Chandregowda, A. Kush and G.C. Reddy, Eur. J. Med. Chem., 44, 2711 (2009).
R.K. Vempati, N.S. Reddy, S.R. Alapati and P.K. Dubey, Der Pharma Chem., 3, 500 (2011).
(a) T. Norris, T.F. Braish, M. Butters, K.M. Devries, J.M. Hawkins, S.S. Masset and P.R. Rose, D. Santafianos and C. Sklavounos, J. Chem. Soc., Perkin Trans. I, 1615 (2000); (b) Q. Sun, R. Zhu, F.W. Foss Jr. and T.L. Macdonald, Bioorg. Med. Chem. Lett., 17, 6682 (2007); (c) G. Madhusudan, V. Balaraju, T. Rajesh, B.V. Narayana and R.N. Reddy, Indian J. Chem., 48B, 569-573 (2009).