A Practical and Efficient Preparation of Key Intermediates in the Synthesis of Praziquantel

Chunhua Yang; Lingzi Zhang; Yang Zheng; Dequn Sun

doi:10.14233/ajchem.2013.14931

Issue

Vol. 25 No. 16 (2013): Vol 25 Issue 16

Issue Published : 9 October 2013

This work is licensed under a Creative Commons Attribution 4.0 International License.

A Practical and Efficient Preparation of Key Intermediates in the Synthesis of Praziquantel

https://doi.org/10.14233/ajchem.2013.14931

Chunhua Yang

Marine College, Shandong University, Weihai, Wenhua West Road, No.180, Weihai 264209, P.R. China

Lingzi Zhang

Marine College, Shandong University, Weihai, Wenhua West Road, No.180, Weihai 264209, P.R. China

Yang Zheng

Marine College, Shandong University, Weihai, Wenhua West Road, No.180, Weihai 264209, P.R. China

Dequn Sun

Marine College, Shandong University, Weihai, Wenhua West Road, No.180, Weihai 264209, P.R. China

Corresponding Author(s) : Dequn Sun

dequn.sun@sdu.edu.cn

Asian Journal of Chemistry, Vol. 25 No. 16 (2013): Vol 25 Issue 16
Article Published : 9 October 2013

Abstract

Praziquantel is the first drug of choice for all worldwide people infected by schistosomiasis. Many tons of praziquantel are needed each year. In this paper, an improved process for preparation of important intermediates to manufacture the praziquantel was reported.

Keywords

Praziquantel Intermediate Preparation

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Yang, C.; Zhang, L.; Zheng, Y.; Sun, D. A Practical and Efficient Preparation of Key Intermediates in the Synthesis of Praziquantel. ajc 2013, 25, 9415-9416.