Synthesis and Fluorescence Properties 2-N-Piperidinopyrazines

Abstract

2-N-Piperidinopyrazine, 2-N-(3-methyl)piperidinopyrazine and 2-N-(4-methyl)piperidinopyrazine were synthesized by reacting 2-chloropyrazine with piperidine, 3-methylpiperidine, 4-methylpiperidine respectively. The structures of these compounds were confirmed by spectroscopic methods. Fluorescence studies were carried out in tetrahydrofuran, acetonitrile, ethyl acetate and ethanol. 2-N-Piperidinopyrazine showed the highest fluorescence intensity in tetrahydrofuran followed by 2-N-4-methylpiperidinopyrazine. The fluorescence intensity decreases as the polarity of the solvent increases.