N-Arylation of Amines with o-Silylaryl Triflate

Y.G. Lee; D.I. Jung; J.T. Hahn

doi:10.14233/ajchem.2013.14423

Issue

Vol. 25 No. 12 (2013): Vol 25 Issue 12

Issue Published : 17 June 2013

This work is licensed under a Creative Commons Attribution 4.0 International License.

N-Arylation of Amines with o-Silylaryl Triflate

https://doi.org/10.14233/ajchem.2013.14423

Y.G. Lee

Department of Chemistry, Dong-A University, Busan 604714, Republic of Korea

D.I. Jung

Department of Chemistry, Dong-A University, Busan 604714, Republic of Korea

J.T. Hahn

Department of Beautycare, Youngdong University, Youngdong 370701, Republic of Korea

Corresponding Author(s) : D.I. Jung

dijung@dau.ac.kr

Asian Journal of Chemistry, Vol. 25 No. 12 (2013): Vol 25 Issue 12
Article Published : 17 June 2013

Abstract

An efficient, transition-metal-free procedure for the N-arylation of amines 1 has been achieved by allowing those substrates to react with o-silylaryl triflate 2 in the presence of CsF. Good to excellent yields of arylated products 3 are obtained under very mild reaction conditions. This chemistry readily tolerates a variety of functional groups.