Cytotoxic Activities of Thiosemicarbazones and Their Metal Complexes

N. Rama Jyothi; N.A. Mohammad Farook; Migyung Cho; Jaesool Shim

doi:10.14233/ajchem.2013.OH106

Issue

Vol. 25 No. 10 (2013): Vol 25 Issue 10

Issue Published : April 29, 2013

This work is licensed under a Creative Commons Attribution 4.0 International License.

Cytotoxic Activities of Thiosemicarbazones and Their Metal Complexes

https://doi.org/10.14233/ajchem.2013.OH106

N. Rama Jyothi

Department of Chemistry, Khadir Mohideen College, Adirampattinam-614 701, India

N.A. Mohammad Farook

Department of Chemistry, Khadir Mohideen College, Adirampattinam-614 701, India

Migyung Cho

School of Mechanical Engineering, Yeungnam University, Gyeongsan-si 712 749, Republic of Korea

Jaesool Shim

School of Mechanical Engineering, Yeungnam University, Gyeongsan-si 712 749, Republic of Korea

Corresponding Author(s) : Migyung Cho

mgcho@tu.ac.kr

Asian Journal of Chemistry, Vol. 25 No. 10 (2013): Vol 25 Issue 10
Article Published : May 3, 2013

Abstract

The cytotoxic properties of thiosemicarbazones and their transition metal complexes are reviewed since 2006.

Keywords

Thiosemicarbazones Cytotoxic Anti-tumor Anti-proliferative

Rama Jyothi, N., Mohammad Farook, N., Cho, M., & Shim, J. (2013). Cytotoxic Activities of Thiosemicarbazones and Their Metal Complexes. Asian Journal of Chemistry, 25(10), 5841–5843. https://doi.org/10.14233/ajchem.2013.OH106

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References

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F.A. French and E.J.Jr. Blanz, Cancer Res., 25, 1454 (1965).
T. Mosmann, J. Immunol Methods, 16, 55 (1983).
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J.A. Lessa, I.C. Mendes, P.R.O. da Silva, M.A. Soares, R.G. dos Santos, N.L. Speziali, N.C. Romeiro, E.J. Barreiro and H. Beraldo, Eur. J. Med. Chem., 45, 5671 (2010).
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T. Stringer, B. Therrien, D.T. Hendricks, H. Guzgay and G.S. Smith, Inorg. Chem. Commun., 14, 956 (2011).
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M.A. Soares, J.A. Lessa, I.C. Mendes, J.D. Da Silva, R.G. dos Santos, L.B. Salum, H. Daghestani, A.D. Andricopulo, B.W. Day, A. Vogt, J.L. Pesquero, W.R. Rocha and H. Beraldo, Bioorg. Med. Chem., 20, 3396 (2012).
S. Datta, D.K. Seth, S. Gangopadhyay, P. Karmakar and S. Bhattacharya, Inorg. Chim. Acta, 392, 118 (2012).
N.C. Saha, C. Biswas,A. Ghorai, U. Ghosh, S.K. Seth and T. Kar, Polyhedron, 34, 1 (2012).
V.M. Leovac, G.A. Bogdanovic, L.S. Jovanovic, L. Joksovic, V. Markovic, M.D. Joksovic, S.M. Dencic, A. Isakovic, I. Markovic, F.W. Heinemann, S. Trifunovic and I. Dalovic, J. Inorg. Biochem., 105, 1413 (2011).
A. Buschini, S. Pinelli, C. Pellacani, F. Giordani, M.B. Ferrari, F. Bisceglie, M. Giannetto, G. Pelosi and P. Tarasconi, J. Inorg. Biochem., 103, 666 (2009).
M. Belicchi-Ferrari, F. Bisceglie, G. Pelosi, S. Pinelli and P. Tarasconi, Polyhedron, 26, 5150 (2007).
M. Belicchi-Ferrari, F. Bisceglie, A. Buschini, S. Franzoni, G. Pelosi, S. Pinelli, P. Tarasconi and M. Tavone, J. Inorg. Biochem., 104, 199 (2010).
D. Kovala-Demertzi, P.N. Yadav, J. Wiecek, S. Skoulika, T. Varadinova and M.A. Demertzis, J. Inorg. Biochem., 100, 1558 (2006).
M. Serda, D.S. Kalinowski,A. Mrozek-Wilczkiewicz, R. Musiol,A. Szurko, A. Ratuszna, N. Pantarat, Z. Kovacevic, A.M. Merlot, D.R. Richardson and J. Polanski, Bioorg. Med. Chem. Lett., 22, 5527 (2012).
V. Vrdoljak, I. Dilovic, M. Rubcic, S. Kraljevic Pavelic, M. Kralj, D. Matkovic-Calogovic, I. Piantanida, P. Novak, A. Rozman and M. Cindric, Eur. J. Med. Chem., 45, 38 (2010).
I. Dilovic, M. Rubcic, V. Vrdoljak, S. Kraljevic Pavelic, M. Kralj, I. Piantanida and M. Cindric, Bioorg. Med. Chem., 16, 5189 (2008).
M.X. Li, C.L. Chen, D. Zhang, J.Y. Niu and B.S. Ji, Eur. J. Med. Chem., 45, 3169 (2010).
D. Kovala-Demertzi, A. Papageorgiou, L. Papathanasis, A. Alexandratos, P. Daleziz, J.R. Miller and M.A. Demertzis, Eur. J. Med. Chem., 44, 1296 (2009).
A. Karakucuk-iyidogan, D. Tasdemir, E.E. Oruc-Emre and J. Balzarini, Eur. J. Med. Chem., 46, 5616 (2011).

References

H. Beraldo and D. Gambino, Mini-Rev. Med. Chem., 4, 31 (2004).

F.A. French and E.J.Jr. Blanz, Cancer Res., 25, 1454 (1965).

T. Mosmann, J. Immunol Methods, 16, 55 (1983).

http://www.dojindo.com/Protocol/Cell_Proliferation_Protocol.pdf

J.A. Lessa, I.C. Mendes, P.R.O. da Silva, M.A. Soares, R.G. dos Santos, N.L. Speziali, N.C. Romeiro, E.J. Barreiro and H. Beraldo, Eur. J. Med. Chem., 45, 5671 (2010).

A.I. Matesanz, C. Hernandez, A. Rodriguez and P. Souza, J. Inorg. Biochem., 105, 1613 (2011).

S. Halder, P. Paul, S.M. Peng, G.H. Lee, A. Mukherjee, S. Dutta, U. Sanyal and S. Bhattacharya, Polyhedron, 45, 177 (2012).

D.S. Raja, N.S.P. Bhuvanesh and K. Natarajan, Eur. J. Med. Chem., 46, 4584 (2011).

M.X. Li, C.L. Chen, C.S. Ling, J. Zhou, B.S. Ji, Y.J. Wu and J.Y. Niu, Bioorg. Med. Chem. Lett., 19, 2704 (2009).

M.X. Li, D. Zhang, L.Z. Zhang, J.Y. Niu and B.S. Ji, J. Organomet. Chem., 696, 852 (2011).

T. Stringer, B. Therrien, D.T. Hendricks, H. Guzgay and G.S. Smith, Inorg. Chem. Commun., 14, 956 (2011).

J.A. Lessa, J.C. Guerra, L.F. de Miranda, C.F.D. Romeiro, J.D. Da Silva, I.C. Mendes, N.L. Speziali, E.M.S. Fagundes and H. Beraldo, J. Inorg. Biochem., 105, 1729 (2011).

M.A. Soares, J.A. Lessa, I.C. Mendes, J.D. Da Silva, R.G. dos Santos, L.B. Salum, H. Daghestani, A.D. Andricopulo, B.W. Day, A. Vogt, J.L. Pesquero, W.R. Rocha and H. Beraldo, Bioorg. Med. Chem., 20, 3396 (2012).

S. Datta, D.K. Seth, S. Gangopadhyay, P. Karmakar and S. Bhattacharya, Inorg. Chim. Acta, 392, 118 (2012).

N.C. Saha, C. Biswas,A. Ghorai, U. Ghosh, S.K. Seth and T. Kar, Polyhedron, 34, 1 (2012).

V.M. Leovac, G.A. Bogdanovic, L.S. Jovanovic, L. Joksovic, V. Markovic, M.D. Joksovic, S.M. Dencic, A. Isakovic, I. Markovic, F.W. Heinemann, S. Trifunovic and I. Dalovic, J. Inorg. Biochem., 105, 1413 (2011).

A. Buschini, S. Pinelli, C. Pellacani, F. Giordani, M.B. Ferrari, F. Bisceglie, M. Giannetto, G. Pelosi and P. Tarasconi, J. Inorg. Biochem., 103, 666 (2009).

M. Belicchi-Ferrari, F. Bisceglie, G. Pelosi, S. Pinelli and P. Tarasconi, Polyhedron, 26, 5150 (2007).

M. Belicchi-Ferrari, F. Bisceglie, A. Buschini, S. Franzoni, G. Pelosi, S. Pinelli, P. Tarasconi and M. Tavone, J. Inorg. Biochem., 104, 199 (2010).

D. Kovala-Demertzi, P.N. Yadav, J. Wiecek, S. Skoulika, T. Varadinova and M.A. Demertzis, J. Inorg. Biochem., 100, 1558 (2006).

M. Serda, D.S. Kalinowski,A. Mrozek-Wilczkiewicz, R. Musiol,A. Szurko, A. Ratuszna, N. Pantarat, Z. Kovacevic, A.M. Merlot, D.R. Richardson and J. Polanski, Bioorg. Med. Chem. Lett., 22, 5527 (2012).

V. Vrdoljak, I. Dilovic, M. Rubcic, S. Kraljevic Pavelic, M. Kralj, D. Matkovic-Calogovic, I. Piantanida, P. Novak, A. Rozman and M. Cindric, Eur. J. Med. Chem., 45, 38 (2010).

I. Dilovic, M. Rubcic, V. Vrdoljak, S. Kraljevic Pavelic, M. Kralj, I. Piantanida and M. Cindric, Bioorg. Med. Chem., 16, 5189 (2008).

M.X. Li, C.L. Chen, D. Zhang, J.Y. Niu and B.S. Ji, Eur. J. Med. Chem., 45, 3169 (2010).

D. Kovala-Demertzi, A. Papageorgiou, L. Papathanasis, A. Alexandratos, P. Daleziz, J.R. Miller and M.A. Demertzis, Eur. J. Med. Chem., 44, 1296 (2009).

A. Karakucuk-iyidogan, D. Tasdemir, E.E. Oruc-Emre and J. Balzarini, Eur. J. Med. Chem., 46, 5616 (2011).

Issue

Vol. 25 No. 10 (2013): Vol 25 Issue 10

Cytotoxic Activities of Thiosemicarbazones and Their Metal Complexes

Corresponding Author(s) : Migyung Cho

Abstract

Keywords

Full Article

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References

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