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Vol. 33 No. 8 (2021): Vol 33 Issue 8, 2021

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Pharmacological and Phytochemical Assessment of Anagallis arvensis L. Leaf Extracts

https://doi.org/10.14233/ajchem.2021.23265
Shaiphali Saxena
Department of Botany, Government Post Graduate College, Manila-263667, India
Pasumarti Bhaskara Rao
Department of Biological Sciences, College of Basic Sciences & Humanities, G.B. Pant University of Agriculture & Technology, Pantnagar-263145, India

Corresponding Author(s) : Shaiphali Saxena

shefalisaxena1192@gmail.com

Asian Journal of Chemistry, Vol. 33 No. 8 (2021): Vol 33 Issue 8, 2021

Abstract

The present study elucidates anti-inflammatory potential and biochemical activity via 2,2′-diphenyl-1-picrylhydrazyl scavenging potential (DPPH), total antioxidant activity (TAA), ferric reducing antioxidant power (FRAP), ferrous chelating activity (FCA), total phenolic content (TPC), total flavonoid content (TFC) of aqua-methanol (AqM) and aqua-acetone (AqA) extracts of Anagallis arvensis L. leaf along with mineral content (AAS) and quantitative phytochemicals (FT-IR and GC-MS). AqM extract exhibited maximum anti-inflammatory activity (82.90 ± 0.91%), DPPH (65.06 ± 1.87%), TAA (46.85 ± 7.32 μg VCE/mg), FRAP (73.82 ± 1.21 μg TE/mg), TPC (104.17 ± 1.41 μg GAE/mg); while AqA showed maximum FCA (64.77 ± 1.61%) and TFC (19.12 ± 1.24 μg QE/mg). FT-IR spectra of AqM extract ranged from 1020.58 to 3853.42 cm-1. The major six phytochemicals investigated through GC-MS were 9-octadecenoic acid (Z)-methylester; 2-hexadecen-1-ol-3,7,11,15-tetramethyl-[R-[R*,R*-(E)]]; methyl elaidate; 2-methoxy-4-vinylphenol; 9-octadecenamide-(Z)-; and benzoic acid 2-hydroxy-phenylmethyl ester exhibiting antioxidant and anti-inflammatory properties. The present investigation characterizes the pharmacognostic and phytochemical profile of A. arvensis leading towards its futuristic significance in pharmaceutical and nutraceutical industries.

Keywords

Anagallis arvensis Anti-inflammation Antioxidants Phytochemicals
Saxena, S., & Bhaskara Rao, P. (2021). Pharmacological and Phytochemical Assessment of Anagallis arvensis L. Leaf Extracts. Asian Journal of Chemistry, 33(8), 1831–1841. https://doi.org/10.14233/ajchem.2021.23265
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References
  1. M.E. Islam, K.M.D. Islam, M.M. Billah, R. Biswas, M.H. Sohrab and S.M. Rahman, Adv. Tradit. Med., 20, 189 (2019); https://doi.org/10.1007/s13596-019-00401-0
  2. S. Kumar, Adv. Appl. Sci. Res., 2, 129 (2011).
  3. M. Saxena, J. Saxena and A. Pradhan, Int. J. Pharm. Sci. Rev. Res., 16, 130 (2012).
  4. J.S. Rad, S.M.H. Alfatemi, M.S. Rad and M. Iriti, J. Biol. Active Prod. Nat., 4, 44 (2014); https://doi.org/10.1080/22311866.2014.890070
  5. Y.P.S. Bajaj, Anagallis arvensis L. (Common Pimpernel): in vitro Culture, Regeneration of Plants, and the Formation of Anagalline and other Saponins, Springer, Berlin, Heidelberg, pp 1-10 (1999).
  6. S.K. Sood and R. Thakur, Herbal Resources of India and Nepal, Scientific Publishers: India (2015).
  7. M. Amoros, B. Fauconnier and R.L. Girre, Antivir. Res., 8, 13 (1987).
  8. V. Lopez, S. Akerreta, E. Casanova, J. García-Mina, R. Cavero and M. Calvo, Pharm. Biol., 46, 602 (2008); https://doi.org/10.1080/13880200802179634
  9. J.R. Soberón, M.A. Sgariglia, A.C. Pastoriza, E.M. Soruco, S.N. Jäger, G.R. Labadie, D.A. Sampietro and M.A. Vattuone, J. Ethnopharmacol., 203, 233 (2017); https://doi.org/10.1016/j.jep.2017.03.056
  10. A. Shakoor, G. Zaib and A. Rahman, Pak. J. Pharm. Sci., 31, 2341 (2018).
  11. H. Saleem, G. Zengin, I. Ahmad, T.T. Htar, R. Naidu, M.F. Mahomoodally and N. Ahemad, Food Res. Int., 137, 109651 (2020); https://doi.org/10.1016/j.foodres.2020.109651
  12. https://sites.google.com/site/efloraofindia/home
  13. https://sites.google.com/site/eflorapantnagar/
  14. K.R. Brain and T.D. Turner, Practical Evaluation of Phytopharmaceuticals, Wright-Science Technical: Bristol, Britain, Eds., 1, pp. 144 p (1975).
  15. W.C. Evans, Trease and Evans Pharmacognosy, WB Sounders Company Ltd., Edn 14, pp 545-546 (1996).
  16. S. Sakat, A.R. Juvekar and M.N. Gambhire, Int. J. Pharm. Pharm. Sci., 2, 146 (2010); https://doi.org/10.1055/s-0029-1234983
  17. R.L. Ngoua-Meye-Misso, C. Sima-Obiang, J.D.C. Ndong, J.P. Ondo, F.O. Abessolo and L.C. Obame-Engonga, Egypt. J. Basic Appl. Sci., 5, 80 (2018); https://doi.org/10.1016/j.ejbas.2017.11.003
  18. W. Brand-Williams, M.E. Cuvelier and C.L.W.T. Berset, LWT Food Sci. Technol., 28, 25 (1995); https://doi.org/10.1016/S0023-6438(95)80008-5
  19. P. Prieto, M. Pineda and M. Aguilar, Anal. Biochem., 269, 337 (1999); https://doi.org/10.1006/abio.1999.4019
  20. I.E.F. Benzie and J.J. Strain, Ann. Biochem., 239, 70 (1996); https://doi.org/10.1006/abio.1996.0292
  21. C.L. Hsu, W. Chen, Y.M. Weng and C.Y. Tseng, Food Chem., 83, 85 (2003); https://doi.org/10.1016/S0308-8146(03)00053-0
  22. K. Wolfe, X. Wu and R.H. Liu, J. Agric. Food Chem., 51, 609 (2003); https://doi.org/10.1021/jf020782a
  23. A. Djeridane, M. Yousfi, B. Nadjemi, D. Boutassouna, P. Stocker and N. Vidal, Food Chem., 97, 654 (2006); https://doi.org/10.1016/j.foodchem.2005.04.028
  24. O.H. Lowry, N.J. Rosebrough, A.L. Farr and R.J. Randall, J. Biol. Chem., 193, 265 (1951); https://doi.org/10.1016/S0021-9258(19)52451-6
  25. C.N. Giannopolitis and S.K. Ries, Plant Physiol., 59, 309 (1977); https://doi.org/10.1104/pp.59.2.309
  26. M. Kar and D. Mishra, Can. J. Bot., 53, 503 (1975); https://doi.org/10.1139/b75-061
  27. K.P. Reddy, S.M. Subhani, P.A. Khan, K.B. Kumar, Plant Cell Physiol., 26, 987 (1985); https://doi.org/10.1093/oxfordjournals.pcp.a077018
  28. M. Kar and D. Mishra, Plant Physiol., 57, 315 (1976); https://doi.org/10.1104/pp.57.2.315
  29. J.K. Moon and T. Shibamoto, J. Agric. Food Chem., 57, 1655 (2009); https://doi.org/10.1021/jf803537k
  30. D. Huang, B. Ou and R.L. Prior, J. Agric. Food Chem., 53, 1841 (2005); https://doi.org/10.1021/jf030723c
  31. D. Gupta, Int. J. Pharm. Sci. Res., 6, 546 (2015).
  32. M. Alam, A.S. Juraimi, M.Y. Rafii, A.A. Hamid, F. Aslani, M.M. Hasan, M. Zainudin, M. Asraf and M. Uddin, Biomed. Res. Int., 2014, 296063 (2014); https://doi.org/10.1155/2014/296063
  33. K. Patel, G.K. Singh and D.K. Patel, Chin. J. Integr. Med., 24, 551 (2018); https://doi.org/10.1007/s11655-014-1960-x
  34. K.L. Vishwakarma and V. Dubey, Emir. J. Food Agric., 23, 554 (2011).
  35. S. Shaheen, M. Ahmad and N. Haroon, Diversity of Edible Wild Plants: Global Perspectives, In: Edible Wild Plants: An Alternative Approach to Food Security, Springer: Cham, pp 59-64 (2017).
  36. S. Verma and R.S. Dubey, Plant Sci., 164, 645 (2003); https://doi.org/10.1016/S0168-9452(03)00022-0
  37. FSAI, The Safety of Vitamins and Minerals in Food SupplementsEstablishing Tolerable Upper Intake Levels and a Risk Assessment Approach for Products Marketed in Ireland, Food Safety Authority of Ireland Scientific Committee Report, Ireland, pp. 1-156 (2018).
  38. D. Janes, D. Kantar, S. Kreft and H. Prosen, Food Chem., 112, 120 (2009); https://doi.org/10.1016/j.foodchem.2008.05.048
  39. V.R. Ravikumar, V. Gopal and T. Sudha, Res. J. Pharm. Biol. Chem. Sci., 3, 391 (2012).
  40. B.V. Raman, S. La, M.P. Saradhi, B.N. Rao, A.N.V. Khrisna and M. Sudhakar, Asian J. Pharm. Clin. Res., 5, 99 (2012).
  41. K. Krishnamoorthy and P. Subramaniam, Int. Sch. Res. Notices, 2014, 567409 (2014); https://doi.org/10.1155/2014/567409
  42. K. Marimuthu, N. Nagaraj and O. Ravi, Int. J. Pharm. Sci. Rev. Res., 27, 63 (2014).
  43. H.A. Hamid, S. Kupan and M.M. Yusoff, Int. J. Food Prop., 20, 674 (2017); https://doi.org/10.1080/10942912.2016.1177071
  44. S. Nagarjunakonda, S. Amalakanti, S.R. Dhishana, M. Ramaiah and L. Rajanala, Pharmacogn. J., 9, 102 (2016); https://doi.org/10.5530/pj.2017.1.17
  45. X. Li, T. Chen, S. Lin, J. Zhao, P. Chen, Q. Ba, H. Guo, Y. Liu, J. Li, R. Chu, L. Shan, W. Zhang and H. Wang, Curr. Cancer Drug Targets, 13, 472 (2013); https://doi.org/10.2174/1568009611313040009
  46. S.N. Shi, J.L. Shi, Y. Liu, Y.L. Wang, C.G. Wang, W.H. Hou and J.Y. Guo, Evid-based Complement. Alternat. Med., 2014, 325948 (2014); https://doi.org/10.1155/2014/325948
  47. G. Selvamangai and A. Bhaskar, Int. J. Drug Dev. Res., 5, 384 (2012).
  48. S. Ira, M. Manisha and G.P. Singh, Int. J. Pharm. Sci. Rev. Res., 33, 315 (2015).
  49. S. Arora and S. Meena, TPI J., 6, 568 (2017).
  50. M.N. Abubakar and R.R. Majinda, Medicines, 3, 3 (2016); https://doi.org/10.3390/medicines3010003
  51. K. Irulandi, S. Geetha, A. Tamilselvan and P. Mehalingam, Asian J. Plant Sci. Res., 6, 24 (2016).
  52. S. Arora and M. Saini, Pharmacognosy Res., 9, S48 (2017); https://doi.org/10.4103/pr.pr_62_17
  53. N. Fagali and A. Catala, Biophys. Chem., 137, 56 (2008); https://doi.org/10.1016/j.bpc.2008.07.001
  54. A. Nishanthini, V.R. Mohan and S. Jeeva, Int. J. Pharm. Sci. Res., 5, 3977 (2014).
  55. A. Elaiyaraja and G. Chandramoha, J. Pharmacogn. Phytochem., 5, 158 (2016).
  56. T. Vinuchakkaravarthy, C.K. Sangeetha and D. Velmurugan, Acta Cryst. E. Struct. Rep. Online, 66, o2207 (2010); https://doi.org/10.1107/S1600536810029673
  57. S. Lalitha, B. Parthipan and V.R. Mohan, Int. J. Pharmacogn. Phytochem. Res., 7, 802 (2015).
  58. P. Liu, X. Liu, F. Lai, L. Ma, W. Li and P. Huang, bioRxiv, 622423 (2019); https://doi.org/10.1101/622423
  59. R. Mechoulam, E. Fride, L. Hanu, T. Sheskin, T. Bisogno, V. Di Marzo, M. Bayewitch and Z. Vogel, Nature, 389, 25 (1997); https://doi.org/10.1038/37891
  60. C. Negut, L. Pintilie, C. Tanase, D.I. Udeanu, C. Draghici, C. Munteanu and E. Morosan, Rev. de Chim., 69, 790 (2018); https://doi.org/10.37358/RC.18.4.6201
  61. B.G. Crandall Jr. and R.W. Emerson, European Patents EP0800344B1 (2003).
  62. https://pubchem.ncbi.nlm.nih.gov/compound/Hexyl-cinnamicaldehyde
  63. T.U. Jayawardena, H.S. Kim, K.A. Sanjeewa, S.Y. Kim, J.R. Rho, Y. Jee, G. Ahn and Y.J. Jeon, Algal Res., 40, 101513 (2019); https://doi.org/10.1016/j.algal.2019.101513
  64. T. Curtis and D.G. Williams, An introduction to perfumery, Micelle Press, Port Washington, NY, USA, Eds. 2 (2008).
  65. https://hmdb.ca/metabolites/HMDB0029818
  66. B.F. Cravatt, R.A. Lerner and D.L. Boger, J. Am. Chem. Soc., 118, 580 (1996); https://doi.org/10.1021/ja9532345
  67. M.C. Cheng, Y.B. Ker, T.H. Yu, L.Y. Lin, R.Y. Peng and C.H. Peng, J. Agric. Food Chem., 58, 1502 (2010); https://doi.org/10.1021/jf903573g
  68. B.R. Kim, H.M. Kim, C.H. Jin, S.Y. Kang, J.B. Kim, Y.G. Jeon, K.Y. Park, I.S. Lee and A.R. Han, Plants, 9, 717 (2020); https://doi.org/10.3390/plants9060717
  69. US EPA, Supporting Information for Low-Priority Substance 1-Eicosanol (CASRN 629-96-9) Final Designation (2020)
  70. S. Tamil Selvi, S. Jamuna, S. Thekan and S. Paulsamy, J. Ayurved. Herbal Med., 3, 63 (2017).
  71. A.I. Dirar, M.A. Mohamed, W.J. Ahmed, M.S. Mohammed, H.S. Khalid and E.A. Garelnabi, J. Pharmacogn. Phytochem., 3, 38 (2014).
  72. V. Malayaman, S. Sheik Mohamed, R.P. Senthilkumar and M. Ghouse Basha, J. Pharmacogn. Phytochem., 8, 2678 (2019).
  73. R. Ashwathanarayana and R. Naika, Asian J. Pharm. Clin. Res., 11, 72 (2018).
  74. I.A. Adebayo, H. Arsad and M.R. Samian, Pharmacogn. Mag., 14, 554 (2018).
  75. M.L. Barr, P.J. Vincenti and R.V. Burke, Composition Deodorante a Base de Acetyl Hexamethyl Tetralin (Tonalide), European Patents EP0714281B1 (2001).
  76. S.N. Ashakirin, M. Tripathy, U.K. Patil and A.B.A. Majeed, Int. J. Pharm. Sci. Res., 8, 2333 (2017);
  77. M.A. Ebrahimzad, S.M. Nabavi and S.F. Nabavi, Pak. J. Biol. Sci., 12, 934 (2009); https://doi.org/10.3923/pjbs.2009.934.938
  78. Z. Yasmeen, Ph.D. Thesis, Phytochemical and Biological Evaluation of Anagallis arvensis, The Islamia University of Bahawalpur, Bahawalpur, Pakistan, p. 5 (2017).
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