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Phytochemical Study of Two Algerian Plants Origanum vulgare L. Sbsp. glandulosum (Desf) Ietswaart and Thymus algeriensis (Boiss. and Reut)
Corresponding Author(s) : Farid Ait Kaki
Asian Journal of Chemistry,
Vol. 31 No. 5 (2019): Vol 31 Issue 5
Abstract
In phytochemical study of two Algerian plants, the ethyl acetate and n-butanol extracts from aerial parts of Origanum vulgare L. Sbsp. glandulosum (Desf) ietswaart and n-butanol extract from aerial parts of Thymus algeriensis (Boiss. and Reut), one flavonoid (8,4'-dihydroxy-7-O-β-D-arabinopyranosideflavone) was isolated for the first time from Origanum vulgare L. Sbsp. glandulosum ethyl acetate extract using chromatographic methods. The structure was identified on the basis of spectral analysis including UV-visible, HPLC-TOF/MS, IR, 1H NMR and 13C NMR. The HPLC-TOF/MS analysis of the two n-butanol plants extracts showed the presence of important compounds such as phenolic acids and flavonoids. The antibacterial assay revealed that the different n-butanol extracts have a weak activity against the tested bacteria.
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References
T.G. Tutin, V.H. Heywood, N.A. Burges, D.M. Moore, D.H. Valentine, S.M. Walters and D.A. Webb, Flora Europaea, Cambridge University Press: Cambridge, vol. 3 (1968).
F.A. Tomas-Barberan, M.I. Gil, F. Ferreres and F. Tomas-Lorente, Phytochemistry, 31, 3097 (1992); https://doi.org/10.1016/0031-9422(92)83452-5.
L. Boulos, Medicinal Plants of North Africa, Reference Publications. Inc: Michigan, USA (1983).
J.H. Ietswaart, A Taxonomic Revision of the Genus Origanum (Labiateae), In: Chemical Composition and Antioxidant Activity of Essential Oils from Algerian Origanum glandulosum Desf, Leiden Botanical, Leiden University Press: La Haye, series 4 (1980).
J. Valnet, Aromathérapie traitement des maladies par les essences des plantes, Maloine S.A.: Paris, edn 10 (1984).
K. Mechergui, W. Jaouadi, J.P. Coelho and M.L. Khouja, Ind. Crops Prod., 90, 32 (2016); https://doi.org/10.1016/j.indcrop.2016.06.011.
A. Jayari, N. El Abed, A. Jouini, O. Mohammed Saed Abdul-Wahab, A. Maaroufi and S. Ben Hadj Ahmed, J. Food Saf., 38, e12409 (2018); https://doi.org/10.1111/jfs.12409.
F. Ait Kaki, R. Benkiniouar, A. Zellagui, S. Rhouati and F. Zaidi, J. Academica, 5, 3 (2015).
R. Benkiniouar, S. Rhouati, A. Touil, E. Seguin and E. Chosson, Chem. Nat. Compd., 43, 321 (2007); https://doi.org/10.1007/s10600-007-0118-x.
G. Abay, M. Altun, S. Koldas, A.R. Tüfekçi and I. Demirtas, Comb. Chem. High Throughput Screen., 18, 453 (2015); https://doi.org/10.2174/1386207318666150305112504.
N. Boutaoui, L. Zaiter, F. Benayache, S. Benayache, S. Carradori, S. Cesa, A.M. Giusti, C. Campestre, L. Menghini, D. Innosa and M. Locatelli, Molecules, 23, 463 (2018); https://doi.org/10.3390/molecules23020463.
K.R. Markham, Techniques of Flavonoid Identification, Academic Press: London (1982).
T.J. Mabry, K.R. Markham and M.B. Thomas, The Systematic Identification of Flavonoids, Springer-Verlag: Berlin (1970).
P.K. Agrawal, Carbon-13 NMR of Flavonoids, Elsevier: New York, edn 1 (1989).
M. Iinuma, S. Matsuura and K. Kusuda, Chem. Pharm. Bull., 28, 708 (1980); https://doi.org/10.1248/cpb.28.708.
P. Joseph-Nathan and R.L. Santillán, Spectrochim. Acta, 40, 1077 (1984); https://doi.org/10.1016/0584-8539(84)80136-1.
K.R. Markham and B. Ternai, Tetrahedron, 32, 2607 (1976); https://doi.org/10.1016/0040-4020(76)88036-2.
H. Wagner, V.M. Chari and J. Sonnenbichler, Tetrahedron Lett., 17, 1799 (1976); https://doi.org/10.1016/S0040-4039(00)93787-0.
J.B. Harborne, The Flavonoids: Advances in Research since 1980, Chapman and Hall: London (1988).
R.S. Tipson and F.S. Parker, Applications of IR spectroscopy in Biochemistry, Biology and Medicine, Hilger: London (1971).
Teacher's Sheet, Spectral Analysis: IR and NMR spectroscopy; https://phychim.ac-versailles.fr/IMG/pdf/Documents-formationspectroscopies.pdf.
I. Ben El Hadj Ali, M. Chaouachi, R. Bahri, I. Chaieb, M. Boussaid and F. Harzallah-Skhiri, Ind. Crops Prod., 77, 631 (2015); https://doi.org/10.1016/j.indcrop.2015.09.046.