Synthesis and Biological Activities of Some New Pyrazolo [3,4-d] Pyrimidine Derivatives

M. Seada; A.M. Abdel-Halim; S.S. Ibrahim; M. Abdel-Megid

Issue

Vol. 4 No. 3 (1992): Vol 4 Issue 3

Issue Published : July 17, 1992

Synthesis and Biological Activities of Some New Pyrazolo [3,4-d] Pyrimidine Derivatives

M. Seada

Chemistry Department, Faculty of Education Ain Shams University, Roxy, Cairo, Egypt

A.M. Abdel-Halim

Chemistry Department, Faculty of Education Ain Shams University, Roxy, Cairo, Egypt

S.S. Ibrahim

Chemistry Department, Faculty of Education Ain Shams University, Roxy, Cairo, Egypt

M. Abdel-Megid

Chemistry Department, Faculty of Education Ain Shams University, Roxy, Cairo, Egypt

Corresponding Author(s) : M. Seada

Asian Journal of Chemistry, Vol. 4 No. 3 (1992): Vol 4 Issue 3
Article Published : March 30, 2010

Abstract

Synthesis of 3-amino-6-methyl-4-phenyl-1H-pyrazolo [3,4-d] pyrimidine (II), which underwent cycloaddition on heating with some vicinal chlorocyanoheterocyclic systems, diethyl malonate, phenacyl bromide and diethyl oxalate. On the other hand, the reactions of (II) with aromatic aldehydes, α-dicarbonyl compounds, α-keto acid and different acylating agents have been investigated.

Keywords

Synthesis Biological Activity Pyrazolo [3,4-d] Pyrimidine Derivatives

Seada, M., Abdel-Halim, A., Ibrahim, S., & Abdel-Megid, M. (2010). Synthesis and Biological Activities of Some New Pyrazolo [3,4-d] Pyrimidine Derivatives. Asian Journal of Chemistry, 4(3), 588–596. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/25100

Issue

Vol. 4 No. 3 (1992): Vol 4 Issue 3

Synthesis and Biological Activities of Some New Pyrazolo [3,4-d] Pyrimidine Derivatives

Corresponding Author(s) : M. Seada

Abstract

Keywords

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