Synthesis of Some New Alkyl Triazolyl Sulphides, Bis-Triazolyl Disulphides, Bis-Triazolyl Ethylene Disulphides and Triazolyl Aryl Dithiocarbamates as Antifungal Agents

Abstract

Several new alkyl triazolyl sulphides (1–12), bis-triazolyl disulphides (13–18), bis-triazolyl ethylene disulphides (19–24) and triazolyl aryl dithiocarbamates (25–48) have been prepared. Most of the compounds have been screened for their antifungal activity against two fungi, viz. Aspergillus niger and Helminthosporium oryzae and found to be antifungal. Based on the screening data, possible structure-activity relationship has been discussed.