Solvent Effects on the Catalytic Hydrolysis of Acetamide by Co-Mo-Oxide Catalyst

Abstract

Solvent effect on the catalytic hydrolysis of acetamide by Co-Mo-oxide catalyst were investigated in glycerol, ethylene glycol and ethanol-water. The used percentages of organic solvent are: 25, 45 and 65% v/v, at 60ºC. The results shown that the reaction follows a second order kinetics in all cases which illustrates that solvents alter the reaction rate without influencing the mechanism. The used polar organic solvents in presence of CoO–MoO₃ catalyst probably leads to a certain type of bond with water molecule. The formation of this bond increases with the polarity of the organic solvent which may led to a decreases in the water activity with increasing the percent of organic solvent. Aslo it was found that the medium of higher dielectric constant D is characterized by higher reaction rate.