Synthesis of 2-, 3- and 4-Carboxyphenoxyacetic Acid: A Necessary Modification
Corresponding Author(s) : Mohini Mohan Adak
Asian Journal of Chemistry,
Vol. 5 No. 2 (1993): Vol 5 Issue 2
Abstract
Selective esterification of aliphatic primary carboxy groups over the aromatic ones within the same framework of a molecule needed 2-, 3- and 4-carboxyphenoxyacetic acids which where synthesised in very good yield, by slight modification of the method introduced hundred years back. Condensed product from chloroacetic acid and corresponding hydroxybenzaldehyde was separated from the mixture as methyl or ethyl ester and subsequently oxidised by alkaline KMnO4. Acidification and usual work up generated the desired products in good quality.
Keywords
Synthesis
2-, 3- and 4-Carboxyphenoxyacetic Acid
Modification
Mohan Adak, M. (2010). Synthesis of 2-, 3- and 4-Carboxyphenoxyacetic Acid: A Necessary Modification. Asian Journal of Chemistry, 5(2), 464–466. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/24836
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