Kinetics and Mechanism of Hydrolysis of Tri-2-chloro-4-Nitrophenyl Phosphate

Abstract

Hydrolysis of tri-2-chloro-4-nitrophenyl phosphate has heen investigated in 20% aqueous-dioxan medium (V/V) at 98ºC in acid region of 0.01–7.0 mol dm³. Acid log rate profile has a rate maxima at 4.0 mol dm³. The lowering in rates after 4.0 mol dm³ may be attributed to the lower ing in concentration of the nucleophile (water activity) or due to negative salt effect or both simultaneously. Ionic strength effect data upto 3.0 μ requires the participation of conjugate acid species and to determine theoretical rates, which are estimated from second empirical terms of Debye Hückel equation, have been found in close aggrement with observed rates.