Synthesis and Biological Studied of 3,4,5-Trimethoxy Benzalanilines

Abstract

Ten Schiff bases of 3,4,5-trimethoxybenzaldehyde have been synthesized by condensing 3,4,5-trimethoxybenzaldehyde with aniline and substituted anilines. The Schiff bases were reduced with sodium borohydride to get secondary amines. All the synthesized compounds were identified and confirmed on the basis of elemental analysis and spectral studies. The synthesized compounds were tested in vitro against five fungi viz., Alternaria tenuis, Ustilago tritici, Sphaeceloma maydis, Puccinia recondita and Alternaria triticina and two nematodes Caenorhabditis elegaus and Ditylenchus myceliophagus. Some of the compounds have shown promising antifungal and nematicidal activity.