Bromination of o-Hydroxyacetophenones and o-Hydroxychalcones with Potassium Bromide-Potassium Bromate
Corresponding Author(s) : B.L. Verma
Asian Journal of Chemistry,
Vol. 8 No. 4 (1996): Vol 8 Issue 4
Abstract
Bromination of o-hydroxyacetophenones (I) and 2' -hydroxychalcones
(IV) with KBr-KBrO3 in glacial acetic acid medium gave corresponding
nuclear substituted 3-bromo-2-hydroxy-acetophenone (II) and
3'-bromo-2'-hydroxychalcone(V) derivatives respectively. However,
bromination of 2'-hydroxy- 5'-methylchalcone (IVc) resulted in 8-bromo-6-
methylflavanone (VI). All the synthesised compounds have been characterised
by elemental analysis and spectral data.
Keywords
Bromination
o-Hydroxyacetophenones
o-Hydroxychalcones
Potassium Bromide-Potassium Bromate
(1)
F. Hussain, K.; Vijayvargiya, D.; Hussain, S.; Verma, B. Bromination of O-Hydroxyacetophenones and O-Hydroxychalcones With Potassium Bromide-Potassium Bromate . ajc 2010, 8, 703-706.
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