Isolation, Characterization and Antimicrobial Activity of Imipramine-Cobalt (II) Complexes

Abstract

A series of seven new coordination compounds of Co(lI) with
imipramine hydrochloride (lPH) has been isolated in non-aqueous
media. The new complexes are characterized by thermal analysis,
IR, electronic spectra, magnetic moments and conductivity measurements.
The IR data suggest that IPH acts as a bidentate ligand.
On the basis of spectral data, an octahedral structure is proposed.
Thermogravimetric studies indicate the presence of water molecule
in the complex. The molar conductance value shows the nonelectrolytic
nature of the complexes. These complexes exhibit enhanced
antimicrobial activity compared to that of free ligand .